Evidence map›Paper›PMID 34255716›Full record

Observational studyJMIR mHealth and uHealth2021

Determining the Evolution of Headache Among Regular Users of a Daily Electronic Diary via a Smartphone App: Observational Study.

Bianca Raffaelli, Jasper Mecklenburg, Lucas Hendrik Overeem, Simon Scholler, Markus A Dahlem, Tobias Kurth, Ana Sofia Oliveira Gonçalves, Uwe Reuter, Lars Neeb

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in JMIR mHealth and uHealth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
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  4. Early Detection of Lower Adherence to Long-Term e-Diary Recording: A Checkpoint to Target Early Educational Intervention in Seasonal Allergic Rhinitis?Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Observational
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  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Bianca RaffaelliDepartment of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0001-9758-1494
Jasper MecklenburgDepartment of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-0777-0038
Lucas Hendrik OvereemDepartment of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0003-2057-7184
Simon SchollerNewsenselab GmbH, Berlin, Germany.ORCID 0000-0003-3428-3494
Markus A DahlemNewsenselab GmbH, Berlin, Germany.ORCID 0000-0002-7532-0127
Tobias KurthInstitute of Public Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0001-7169-2620
Ana Sofia Oliveira GonçalvesInstitute of Public Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-5678-4137
Uwe ReuterDepartment of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-8527-0725
Lars NeebDepartment of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-1940-6399
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmartphone-based apps represent a major development in health care management. Specifically in headache care, the use of electronic headache diaries via apps has become increasingly popular. In contrast to the soaring volume of available data, scientific use of these data resources is sparse.

objectiveIn this analysis, we aimed to assess changes in headache and migraine frequency, headache and migraine intensity, and use of acute medication among people who showed daily use of the headache diary as implemented in the freely available basic version of the German commercial app, M-sense.

methodsThe basic version of M-sense comprises an electronic headache diary, documentation of lifestyle factors with a possible impact on headaches, and evaluation of headache patterns. This analysis included all M-sense users who had entered data into the app on a daily basis for at least 7 months.

resultsWe analyzed data from 1545 users. Mean MHD decreased from 9.42 (SD 5.81) at baseline to 6.39 (SD 5.09) after 6 months (P<.001; 95% CI 2.80-3.25). MMD, AMD, and migraine intensity were also significantly reduced. Similar results were found in 985 users with episodic migraine and in 126 users with chronic migraine.

conclusionsAmong regular users of an electronic headache diary, headache and migraine frequency, in addition to other headache characteristics, improved over time. The use of an electronic headache diary may support standard headache care.

Indexed as

Migraine DisordersMobile ApplicationsElectronicsHeadacheHumansSmartphoneappelectronic diaryfrequencyheadacheheadache appintensitymigrainemobile apppain

Identifiers

PMID34255716
PMCPMC8295831
OpenAlexW3182437134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.