Evidence map›Paper›PMID 34255372›Full record

ArticleSynapse (New York, N.Y.)2021

Acute Delta 9-tetrahydrocannabinol administration differentially alters the hippocampal opioid system in adult female and male rats.

Kyle A Windisch, Sanoara Mazid, Megan A Johnson, Elina Ashirova, Yan Zhou, Lennox Gergoire, Sydney Warwick, Bruce S McEwen, Mary Jeanne Kreek, Teresa A Milner

Open access · greenAbstract read
In one paragraph

Article in Synapse (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kyle A WindischThe Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, New York.ORCID 0000-0002-7713-4512
Sanoara MazidFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York.
Megan A JohnsonFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York.
Elina AshirovaFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York.
Yan ZhouThe Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, New York.
Lennox GergoireFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York.
Sydney WarwickFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York.
Bruce S McEwenHarold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York.
Mary Jeanne KreekThe Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, New York.
Teresa A MilnerThe Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, New York.ORCID 0000-0002-0458-6569
Cornell University · USRockefeller University · US

Funding

ULTRASTRUCTURAL INTERACTIONS OF OPIOIDS IN HIPPOCAMPUSR01DA008259 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI MILNER, TERESA A · 1993 to 2019
$6.4M
Contribution of G protein coupled estrogen receptor to changes in hypothalamic plasticity and hypertension susceptibility in mice with accelerated ovarian failureR01HL136520 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MICHAEL J GLASS, Teresa A Milner · 2017 to 2026
$5.0M
STRESS, ADRENAL STEROIDS AND THE BRAINR01MH041256 · NIMH · ROCKEFELLER UNIVERSITY · PI MCEWEN, BRUCE S. · 1986 to 2015
$4.3M
MENOPAUSAL CHANGES IN HYPOTHALAMUS AND HYPERTENSION SUSCEPTIBILITYR01HL098351 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MILNER, TERESA A · 2011 to 2014
$1.7M
STRESS, ADRENAL STEROIDS AND THE BRAINR37MH041256 · NIMH · ROCKEFELLER UNIVERSITY · PI MCEWEN, BRUCE S. · 1994 to 2003
$1.3M
NHLBI NIH HHS R01 HL098351NHLBI NIH HHS R01 HL136520NIDA NIH HHS R01 DA008259NIMH NIH HHS R01 MH041256NIMH NIH HHS R37 MH041256
6 · The paper itself

Abstract

Our prior studies demonstrated that the rat hippocampal opioid system can undergo sex-specific adaptations to external stimuli that can influence opioid-associated learning processes. This opioid system extensively overlaps with the cannabinoid system. Moreover, acute administration of Δ

Indexed as

Analgesics, OpioidDronabinolAnimalsFemaleHippocampusMaleRatsRats, Sprague-DawleyReceptors, Opioid, deltaReceptors, Opioid, muAnalgesics, OpioidDronabinolReceptors, Opioid, deltaReceptors, Opioid, mudelta opioid receptorhippocampal CA3sex differencesΔ9-tetrahydrocannabinol

Identifiers

PMID34255372
PMCPMC8390442
OpenAlexW3177759232

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.