Evidence map›Paper›PMID 34255249›Full record

ArticleMolecular neurobiology2021

Antioxidative and Anti-inflammatory Effects of Kojic Acid in Aβ-Induced Mouse Model of Alzheimer's Disease.

Amjad Khan, Tae Ju Park, Muhammad Ikram, Sareer Ahmad, Riaz Ahmad, Min Gi Jo, Myeong Ok Kim

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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  9. Neuromelanin-induced cellular stress and neurotoxicity in the pathogenesis of Parkinson's disease.Apoptosis : an international journal on programmed cell death · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Amjad KhanDivision of Applied Life Science (BK 21 Four), College of Natural Sciences, Gyeongsang National University, Jinju, 52828, Republic of Korea.
Tae Ju ParkHaemato-Oncology/Systems Medicine Group, Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, MVLS, University of Glasgow, Glasgow, UK.
Muhammad IkramDivision of Applied Life Science (BK 21 Four), College of Natural Sciences, Gyeongsang National University, Jinju, 52828, Republic of Korea.
Sareer AhmadDivision of Applied Life Science (BK 21 Four), College of Natural Sciences, Gyeongsang National University, Jinju, 52828, Republic of Korea.
Riaz AhmadDivision of Applied Life Science (BK 21 Four), College of Natural Sciences, Gyeongsang National University, Jinju, 52828, Republic of Korea.
Min Gi JoDivision of Applied Life Science (BK 21 Four), College of Natural Sciences, Gyeongsang National University, Jinju, 52828, Republic of Korea.
Myeong Ok KimDivision of Applied Life Science (BK 21 Four), College of Natural Sciences, Gyeongsang National University, Jinju, 52828, Republic of Korea. mokim@gnu.ac.kr.ORCID http://orcid.org/0000-0003-2492-5369
Gyeongsang National University · KRBlood Cancer UK · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a common cause of dementia that is clinically characterized by the loss of memory and cognitive functions. Currently, there is no specific cure for the management of AD, although natural compounds are showing promising therapeutic potentials because of their safety and easy availability. Herein, we evaluated the neuroprotective properties of kojic acid (KA) in an AD mouse model. Intracerebroventricular injection (i.c.v) of Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsAnti-Inflammatory AgentsAntioxidantsCell LineInjections, IntraventricularMaleMiceMice, Inbred C57BLPeptide FragmentsPyronesReactive Oxygen SpeciesTreatment OutcomeAmyloid beta-Peptidesamyloid beta-protein (1-42)Anti-Inflammatory AgentsAntioxidantskojic acidPeptide FragmentsPyronesReactive Oxygen SpeciesAlzheimer’s diseaseKojic acidNeurodegenerationNeuroinflammationOxidative stress

Identifiers

PMID34255249
OpenAlexW3178409791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.