Evidence map›Paper›PMID 34255238›Full record

Trial reportOdontology2022

Arrest of root caries with an adjuvant chlorhexidine-fluoride varnish over a 12-months observation period: a QLF-analyzed, placebo-controlled, randomized, clinical trial (RCT).

Kyung-Jin Park, Thomas Meißner, Elena Günther, Gerhard Schmalz, Tanja Kottmann, Felix Krause, Rainer Haak, Dirk Ziebolz

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Odontology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Oral hygiene agents at work: effects onFrontiers in cellular and infection microbiology · 2026
    Review
  4. Article
  5. Article
  6. Phage TargetingAntibiotics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kyung-Jin Park *Department of CariologyEndodontology and Periodontology, University Leipzig, Liebigstr. 12, 04103, Leipzig, Germany.
Thomas Meißner *Department of CariologyEndodontology and Periodontology, University Leipzig, Liebigstr. 12, 04103, Leipzig, Germany.
Elena GüntherDepartment of Prosthodontics, University Leipzig, Leipzig, Germany.
Gerhard SchmalzDepartment of CariologyEndodontology and Periodontology, University Leipzig, Liebigstr. 12, 04103, Leipzig, Germany.
Tanja KottmannCRO Dr. Med. Kottmann GmbH & Co. KG, Hamm, Germany.
Felix KrauseDepartment of Operative Dentistry, Periodontology and Preventive Dentistry, RWTH Aachen University, Aachen, Germany.
Rainer HaakDepartment of CariologyEndodontology and Periodontology, University Leipzig, Liebigstr. 12, 04103, Leipzig, Germany.
Dirk ZiebolzDepartment of CariologyEndodontology and Periodontology, University Leipzig, Liebigstr. 12, 04103, Leipzig, Germany. dirk.ziebolz@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0002-9810-2368

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed at evaluating the effectiveness of an adjuvant chlorhexidine-fluoride varnish (Cervitec F) for prevention and arrest of root caries on elderly participants using quantitative light-induced fluorescence (QLF). 23 participants with two or three non-cavitated root carious lesions were included and assigned to three groups of different varnishes (CF: Cervitec F, P: placebo, DP: Duraphate). Agents were applied once to root surface at baseline and in follow-up after 3, 6 and 9 months. The lesions were assessed clinically and with QLF. QLF-images were analyzed regarding fluorescence loss (ΔF), lesion volume (ΔQ) and bacterial activity (ΔR) before (t

Indexed as

Dental CariesQuantitative Light-Induced FluorescenceRoot CariesAgedCariostatic AgentsChlorhexidineFluoridesFluorides, TopicalHumansCariostatic AgentsChlorhexidineFluoridesFluorides, TopicalChlorhexidine–fluoride varnishClinical trialQuantitative light-induced fluorescenceRoot caries

Identifiers

PMID34255238
PMCPMC8732822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.