Evidence map›Paper›PMID 34255209›Full record

ReviewCurrent rheumatology reports2021

Advances in Juvenile Spondyloarthritis.

Hemalatha Srinivasalu, Erin Brennan Treemarcki, Christopher Redmond

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Hemalatha SrinivasaluDivision of Rheumatology, Children's National Hospital, George Washington University School of Medicine, 111 Michigan Avenue NW, Washington, DC, 20010, USA. hsriniva@childrensnational.org.ORCID 0000-0001-6714-4170
Erin Brennan TreemarckiDivision of Rheumatology, Department of Pediatrics, University of Utah School of Medicine, 81 N Mario Capecchi Drive, 4th Floor, Salt Lake City, UT, 84113, USA.ORCID 0000-0003-3858-7065
Christopher RedmondDivision of Rheumatology, Children's National Hospital and National Institute of Arthritis and Musculoskeletal and Skin Diseases, Building 10 10N-311, 9000 Rockville Pike, Bethesda, MD, 20892, USA.ORCID 0000-0002-9972-4329
Children's National · USNational Institute of Arthritis and Musculoskeletal and Skin Diseases · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo provide an overview of recent studies on pathogenesis, diagnosis, and management of juvenile spondyloarthritis (JSpA). RECENT

findingsRecent studies show differences in gut microbiome in patients with JSpA in comparison to healthy controls. There is increased recognition of the impact of the innate immune system on disease pathology. Normative reference on MRI of sacroiliac (SI) joints in children is now available. However, there is significant variability in interpretation of MRI of SI joints in children and a need for standardization. NSAIDs, physical therapy, and Tumor Necrosis Factor Inhibitors (TNFi) remain the mainstay of management for patients with JIA who have polyarthritis, sacroiliitis, and/or enthesitis as per recent ACR guidelines. Newer therapeutic options beyond TNFi are needed to manage patients who fail TNFi. This review highlights some of the recent advances in our knowledge of JSpA pathophysiology, diagnosis, and treatment. It also identifies areas in need of further research and standardization to improve our understanding and outcomes in JSpA.

Indexed as

Arthritis, JuvenileSacroiliitisSpondylitis, AnkylosingChildHumansMagnetic Resonance ImagingSacroiliac JointDiagnostic ImagingEnthesitis related arthritisJuvenile Idiopathic ArthritisJuvenile Psoriatic ArthritisPathogenesisTherapy

Identifiers

PMID34255209
OpenAlexW3178163033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.