ArticleInternational journal of implant dentistry2021
Clinical long-term and patient-reported outcomes of dental implants in oral cancer patients.
Article in International journal of implant dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07128134 (Evaluation of the Effects of the Low-level Laser Therapy as an Adjunct to Nonsurgical Treatment in Patients With Periimplantitis), which is not on this map. Cited by 17 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Effects of the Low-level Laser Therapy as an Adjunct to Nonsurgical Treatment in Patients With Periimplantitis
Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Impact of novel systemic cancer therapies on osseointegration and dental implant outcomes: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Survival rate and risk factors of implants in patients with head and neck neoplasms: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Comprehensive Update on Implants in Patients With Head and Neck Cancer (2021-2024): Systematic Review and Meta-Analysis of the Impact of Radiotherapy and Chemotherapy on Implant Survival.Clinical oral implants research · 2025Pooled it
- Efficacy of Oral Rehabilitation Techniques in Patients With Oral Cancer: A Systematic Review and Meta-Analysis.Journal of surgical oncology · 2025Pooled it
- Survival of dental implants in irradiated head and neck cancer patients compared to non-irradiated patients: An umbrella review.PloS one · 2025Pooled it
- Dental implant rehabilitation after jaw tumor resection: a mini-review of protocols and quality of life across treatment modalities.Annals of medicine and surgery (2012) · 2026Article
- Long term dental implant survival and bone level changes with special emphasis on radiation therapy after free fibula flap reconstruction - a retrospective study.Clinical oral investigations · 2025Article
- Implant-Supported Oral Rehabilitation in Head and Neck Cancer Patients: A 20-Year Single-Center Study (2005-2024).Journal of clinical medicine · 2025Article
- Effect of Crestal Position on Bone-Implant Stress Interface of Three-Implant Splinted Prostheses: A Finite Element Analysis.Materials (Basel, Switzerland) · 2025Article
- Assessment of Radiation Attenuation Properties in Dental Implants Using Monte Carlo Method.Bioengineering (Basel, Switzerland) · 2025Article
- Full-Mouth Digital Dental Rehabilitation Under General Anesthesia in a Post-Treatment Intraoral Squamous Cell Carcinoma Patient: A Case Report.Healthcare (Basel, Switzerland) · 2025Article
- A review of interaction of radiotherapy and implants in head and neck cancer - implications and strategies to improve outcomes.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025Review
- Outcomes and influencing factors of dental implants in fibula, iliac crest, and scapula free flaps: a retrospective case-control study.International journal of implant dentistry · 2024Article
- Oral rehabilitation and associated quality of life following mandibular reconstruction with free fibula flap: a cross-sectional study.Frontiers in oncology · 2024Article
- How does dental implant macrogeometry affect primary implant stability? A narrative review.International journal of implant dentistry · 2023Review
- Short versus Standard Length Implants with Sinus Floor Elevation for the Atrophic Posterior Maxilla.Acta stomatologica Croatica · 2022Article
- Osseointegration of a New, Ultrahydrophilic and Nanostructured Dental Implant Surface: A Comparative In Vivo Study.Biomedicines · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe aim of this clinical study was to investigate the clinical long-term and patient-reported outcome of dental implants in patients with oral cancer. In addition, analysis of the influence of radiation therapy, timing of implant insertion, and augmentation procedures on implant survival was performed. MATERIAL AND
methodsThis retrospective study investigated the clinical outcome of 711 dental implants in 164 oral cancer patients, inserted by experienced surgeons of the Department of Oral and Maxillofacial Surgery, University Medical Center Mainz, Germany. Oral health-related quality of life (OHRQoL) was evaluated.
resultsCumulative 5-year and 10-year implant survival rates for all included implants were 87.3% and 80.0%. Implants placed straight after ablative surgery (primary implant placement) and implants placed after completing the oncologic treatment (secondary implant placement) showed a comparable implant survival (92.5% vs. 89.5%; p = 0.635). Irradiation therapy had no significant influence on implant survival of secondary placed implants (p = 0.929). However, regarding implant site (native bone vs. augmented bone) and radiation therapy (non-irradiated bone vs. irradiated bone), implants inserted in irradiated bone that received augmentation procedures showed a statistically significant lower implant survival (p < 0.001). Patients reported a distinct improvement in OHRQoL.
conclusionsPromising long-term survival rates of dental implants in patients after treatment of oral cancer were seen. In addition, patients benefit in form of an improved OHRQoL. However, bone augmentation procedures in irradiated bone may result in an impaired implants' prognosis.
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