ArticleEuropean radiology2022
Coronary calcium scoring potential of large field-of-view spectral photon-counting CT: a phantom study.
Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 66 citations in OpenAlex.
- Quantification of plaque and detection of high-risk plaque characteristics based on coronary computed tomography angiography: comparison between superresolution deep learning reconstruction and hybrid iterative reconstruction.Quantitative imaging in medicine and surgery · 2026Article
- Management of Calcified Coronary Lesions-A Review of Plaque Modification Methods.Journal of clinical medicine · 2025Review
- Impact of vessel size, dose levels, and body habitus on iodine quantification in cardiovascular photon-counting computed tomography.The British journal of radiology · 2025Article
- Influence of deep learning-based super-resolution reconstruction on Agatston score.European radiology · 2025Article
- Ultra-high-resolution 40 keV virtual monoenergetic imaging using spectral photon-counting CT in high-risk patients for coronary stenoses.European radiology · 2025Article
- Photon-counting CT in cancer radiotherapy: technological advances and clinical benefits.Physics in medicine and biology · 2025Review
- Value of Ultrahigh-Resolution Photon-Counting Detector Computed Tomography in Cardiac Imaging.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Photon-counting detector computed tomography in cardiac imaging.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024Review
- Technical principles, benefits, challenges, and applications of photon counting computed tomography in coronary imaging: a narrative review.Cardiovascular diagnosis and therapy · 2024Review
- Charting the Unseen: How Non-Invasive Imaging Could Redefine Cardiovascular Prevention.Journal of cardiovascular development and disease · 2024Review
- Coronary artery calcium quantification technique using dual energy material decomposition: a simulation study.The international journal of cardiovascular imaging · 2024Article
- Reply to the Letter to the Editor: Quantitative accuracy of virtual monoenergetic images from multi-energy CT.European radiology · 2024Article
- Spectral Photon-Counting Computed Tomography: Technical Principles and Applications in the Assessment of Cardiovascular Diseases.Journal of clinical medicine · 2024Review
- Imaging biomarkers in cardiac CT: moving beyond simple coronary anatomical assessment.La Radiologia medica · 2024Review
- Photon-counting detector CT allows significant reduction in radiation dose while maintaining image quality and noise on non-contrast chest CT.European journal of radiology open · 2023Article
- Technical note: Exploring the detectability of coronary calcification using ultra-high-resolution photon-counting-detector CT.Medical physics · 2023Article
- Clinical Applications of Photon-counting CT: A Review of Pioneer Studies and a Glimpse into the Future.Radiology · 2023Review
- Cardiovascular Applications of Photon-Counting CT Technology: A Revolutionary New Diagnostic Step.Journal of cardiovascular development and disease · 2023Review
- Virtual monochromatic images for coronary artery imaging with a spectral photon-counting CT in comparison to dual-layer CT systems: a phantom and a preliminary human study.European radiology · 2023Article
- Virtual monochromatic images for coronary artery imaging with a spectral photon-counting CT in comparison to dual-layer CT systems: a phantom and a preliminary human study.European radiology · 2023Article
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Authors and funding
11 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the current study was, first, to assess the coronary artery calcium (CAC) scoring potential of spectral photon-counting CT (SPCCT) in comparison with computed tomography (CT) for routine clinical protocols. Second, improved CAC detection and quantification at reduced slice thickness were assessed.
methodsRaw data was acquired and reconstructed with several combinations of reduced slice thickness and increasing strengths of iterative reconstruction (IR) for both CT systems with routine clinical CAC protocols for CT. Two CAC-containing cylindrical inserts, consisting of CAC of different densities and sizes, were placed in an anthropomorphic phantom. A specific CAC was detectable when 3 or more connected voxels exceeded the CAC scoring threshold of 130 Hounsfield units (HU). For all reconstructions, total CAC detectability was compared between both CT systems. Significant differences in CAC quantification (Agatston and volume scores) were assessed with Mann-Whitney U tests. Furthermore, volume scores were compared with the known CAC physical.
resultsCAC scores for routine clinical protocols were comparable between SPCCT and CT. SPCCT showed 34% and 4% higher detectability of CAC for the small and large phantom, respectively. At reduced slice thickness, CAC detection increased by 142% and 169% for CT and SPCCT, respectively. In comparison with CT, volume scores from SPCCT were more comparable with the physical volume of the CAC.
conclusionCAC scores using routine clinical protocols are comparable between conventional CT and SPCCT. The increased spatial resolution of SPCCT allows for increased detectability and more accurate CAC volume estimation. KEY POINTS: • Coronary artery calcium scores using routine clinical protocols are comparable between conventional CT and spectral photon-counting CT. • In comparison with conventional CT, increased coronary artery calcium detectability was shown for spectral photon-counting CT due to increased spatial resolution. • Volumes scores were more accurately determined with spectral photon-counting CT.
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