Evidence map›Paper›PMID 34254850›Full record

ArticleRadiology2021

Pulmonary Embolism in Hospitalized Patients with COVID-19: A Multicenter Study.

Sadjad Riyahi, Hreedi Dev, Ashkan Behzadi, Jinhye Kim, Hanieh Attari, Syed I Raza, Daniel J Margolis, Ari Jonisch, Ayah Megahed, Anas Bamashmos and 2 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
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  7. Observational
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  13. COVID-19: a multi-organ perspective.Frontiers in cellular and infection microbiology · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Sadjad RiyahiFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).ORCID 0000-0002-7212-223X
Hreedi DevFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).ORCID 0000-0002-5341-8350
Ashkan BehzadiFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).ORCID 0000-0002-2163-3662
Jinhye KimFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).
Hanieh AttariFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).ORCID 0000-0001-8393-3735
Syed I RazaFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).ORCID 0000-0001-7722-9207
Daniel J MargolisFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).ORCID 0000-0001-8212-707X
Ari JonischFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).
Ayah MegahedFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).ORCID 0000-0002-1912-1553
Anas BamashmosFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).ORCID 0000-0002-0448-4204
Kareem ElfatairyFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).ORCID 0000-0002-3254-9271
Martin R PrinceFrom the Departments of Radiology of Weill Cornell Medicine, 416 E 55th St, New York, NY 10022 (S.R., H.D., J.K., H.A., S.I.R., D.J.M., A.J., M.R.P.); Bridgeport Hospital, Yale New Haven Health System, Bridgeport, Conn (A. Behzadi, A.M., A. Bamashmos, K.E.); and Columbia College of Physicians and Surgeons, New York, NY (M.R.P.).ORCID 0000-0002-9883-0584
Cornell University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
NCATS NIH HHS UL1 TR000457NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Background Pulmonary embolism (PE) commonly complicates SARS-CoV-2 infection, but incidence and mortality reported in single-center studies, along with risk factors, vary. Purpose To determine the incidence of PE in patients with COVID-19 and its associations with clinical and laboratory parameters. Materials and Methods In this HIPAA-compliant study, electronic medical records were searched retrospectively for demographic, clinical, and laboratory data and outcomes among patients with COVID-19 admitted at four hospitals from March through June 2020. PE found at CT pulmonary angiography and perfusion scintigraphy was correlated with clinical and laboratory parameters. The d-dimer level was used to predict PE, and the obtained threshold was externally validated among 85 hospitalized patients with COVID-19 at a fifth hospital. The association between right-sided heart strain and embolic burden was evaluated in patients with PE undergoing echocardiography. Results A total of 413 patients with COVID-19 (mean age, 60 years ± 16 [standard deviation]; age range, 20-98 years; 230 men) were evaluated. PE was diagnosed in 102 (25%; 95% CI: 21, 29) of 413 hospitalized patients with COVID-19 who underwent CT pulmonary angiography or perfusion scintigraphy. PE was observed in 21 (29%; 95% CI: 19, 41) of 73 patients in the intensive care unit (ICU) versus 81 (24%; 95% CI: 20, 29) of 340 patients who were not in the ICU (

Indexed as

AdultAgedAged, 80 and overCohort StudiesComorbidityComputed Tomography AngiographyCOVID-19FemaleHospitalizationHumansIncidenceInpatientsMaleMiddle AgedNew York CityPulmonary Artery

Identifiers

PMID34254850
PMCPMC8294351
OpenAlexW3177875708

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.