ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021
Early success transplanting kidneys from donors with new SARS-CoV-2 RNA positivity: A report of 10 cases.
Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Solid organ transplantation from donors with recent or current SARS-CoV-2 infection: A systematic review.Anaesthesia, critical care & pain medicine · 2022Pooled it
- Utilization and outcomes of COVID-19 positive donors in pediatric kidney transplantation-a population-based study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Testing of tissue specimens obtained from SARS-CoV-2 nasopharyngeal swab-positive donors.Cell and tissue banking · 2024Article
- Review
- Utilization of COVID-19 positive donors for Heart transplantation and associated short-term outcomes.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023Article
- Medicine Faculty Students' Perspective on Cadaver and Organ Donation in the COVID-19 Pandemic.Transplantation proceedings · 2023Article
- Coronavirus Disease-2019 and Implications on the Liver.Clinics in liver disease · 2023Review
- Successful lung transplantation using an allograft from a COVID-19-recovered donor: a potential role for subgenomic RNA to guide organ utilization.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023Article
- A new chapter in an evolving pandemic: Successful pediatric liver transplantation with SARS-CoV-2+ donors.Pediatric transplantation · 2022Article
- Comparative outcomes for over 100 deceased donor kidney transplants from SARS-CoV-2 positive donors: A single-center experience.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022Article
- [Update of the recommendations on the management of the SARS-CoV-2 coronavirus pandemic (COVID-19) in kidney transplant patients.]Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia · 2022Review
- COVID-19 positive donor for solid organ transplantation.Journal of hepatology · 2022Review
- COVID-19 in donation and transplant.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022Review
- Recommendations for Evaluation and Selection of Deceased Organ Donor: Position Statement of ISCCM.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
- Organ transplantation using COVID-19-positive deceased donors.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022Article
- Utilization and outcomes of deceased donor SARS-CoV-2-positive organs for solid organ transplantation in the United States.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022Article
- Short-term kidney transplant outcomes from severe acute respiratory syndrome coronavirus 2 lower respiratory tract positive donors.Transplant infectious disease : an official journal of the Transplantation Society · 2022Article
- Liver transplantation from active COVID-19 donors: Is it ethically justifiable?Transplant infectious disease : an official journal of the Transplantation Society · 2022Article
- The Global Impact of COVID-19 on Solid Organ Transplantation: Two Years Into a Pandemic.Transplantation · 2022Review
- Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Transmission Through Solid Organ Transplantation and Outcomes of Coronavirus Disease 2019 Among Recent Transplant Recipients.Open forum infectious diseases · 2022Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transplantation of solid organs from donors with active SARS-CoV-2 infection has been advised against due to the possibility of disease transmission to the recipient. However, with the exception of lungs, conclusive data for productive infection of transplantable organs do not exist. While such data are awaited, the organ shortage continues to claim thousands of lives each year. In this setting, we put forth a strategy to transplant otherwise healthy extrapulmonary organs from SARS-CoV-2-infected donors. We transplanted 10 kidneys from five deceased donors with new detection of SARS-CoV-2 RNA during donor evaluation in early 2021. Kidney donor profile index ranged from 3% to 56%. All organs had been turned down by multiple other centers. Without clear signs or symptoms, the veracity of timing of SARS-CoV-2 infection could not be confirmed. With 8-16 weeks of follow-up, outcomes for all 10 patients and allografts have been excellent. All have been free of signs or symptoms of donor-derived SARS-CoV-2 infection. Our findings raise important questions about the nature of SARS-CoV-2 RNA detection in potential organ donors and suggest underutilization of exceptionally good extrapulmonary organs with low risk for disease transmission.
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