Evidence map›Paper›PMID 34254423›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2022

Lung transplantation for acute respiratory distress syndrome: A multicenter experience.

Anna E Frick, Christiaan T Gan, Robin Vos, Stefan Schwarz, Felix Kraft, Daria Kifjak, Arne P Neyrinck, Dirk E Van Raemdonck, Walter Klepetko, Peter Jaksch and 2 more

Abstract readMulticenter Study
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Chronic Lung Allograft Dysfunction in Patients Receiving Lung Transplantation for COVID-19 ARDS.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Article
  10. Review
  11. Infectious Complications of Lung Transplant for Coronavirus Disease 2019-Associated Lung Injury: A Single-Center Case-Control Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  12. Article
  13. Article
  14. Gamma-glutamyltransferase is a strong predictor of secondary sclerosing cholangitis after lung transplantation for COVID-19 ARDS.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2022
    Article
  15. Article
  16. Lung transplant for COVID-19-a bone of contention!Indian journal of thoracic and cardiovascular surgery · 2022
    Article
  17. Review
  18. Review
  19. Article
  20. Lung transplantation for acute respiratory distress syndrome: A multicenter experience.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anna E FrickDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-2959-2137
Christiaan T GanDepartment of Pulmonary Diseases, University Medical Centre Groningen, Groningen, The Netherlands.
Robin VosBREATHE, Leuven Lung Transplant Unit, Department of Chronic Diseases, Metabolism and Ageing (Chromed), KU Leuven, Leuven, Belgium.ORCID 0000-0002-3468-9251
Stefan SchwarzDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-3570-0766
Felix KraftDepartment of Anaesthesia, General Intensive Care and Pain Management, Medical University of Vienna, Vienna, Austria.
Daria KifjakDepartment of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.
Arne P NeyrinckDepartment of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
Dirk E Van RaemdonckBREATHE, Leuven Lung Transplant Unit, Department of Chronic Diseases, Metabolism and Ageing (Chromed), KU Leuven, Leuven, Belgium.ORCID 0000-0003-1261-0992
Walter KlepetkoDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Peter JakschDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Erik A M VerschuurenDepartment of Pulmonary Diseases, University Medical Centre Groningen, Groningen, The Netherlands.
Konrad HoetzeneckerDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-6775-7460

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute respiratory distress syndrome (ARDS) is a rapidly progressive lung disease with a high mortality rate. Although lung transplantation (LTx) is a well-established treatment for a variety of chronic pulmonary diseases, LTx for acute lung failure (due to ARDS) remains controversial. We reviewed posttransplant outcome of ARDS patients from three high-volume European transplant centers. Demographics and clinical data were collected and analyzed. Viral infection was the main reason for ARDS (n = 7/13, 53.8%). All patients were admitted to ICU and required mechanical ventilation, 11/13 were supported with ECMO at the time of listing. They were granted a median LAS of 76 (IQR 50-85) and waited for a median of 3 days (IQR 1.5-14). Postoperatively, median length of mechanical ventilation was 33 days (IQR 17-52.5), median length of ICU and hospital stay were 39 days (IQR 19.5-58.5) and 54 days (IQR 43.5-127). Prolongation of peripheral postoperative ECMO was required in 7/13 (53.8%) patients with a median duration of 2 days (IQR 2-7). 30-day mortality was 7.7%, 1 and 5-year survival rates were calculated as 71.6% and 54.2%, respectively. Given the lack of alternative treatment options, the herein presented results support the concept of offering live-saving LTx to carefully selected ARDS patients.

Indexed as

Lung TransplantationRespiratory Distress SyndromeHumansLength of StayLungRespiration, Artificialclinical research/practicehealth services and outcomes researchlung (allograft) function/dysfunctionlung failure/injurylung transplantation/pulmonology

Identifiers

PMID34254423
PMCPMC8441742

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.