Evidence map›Paper›PMID 34254184›Full record

ArticleSurgical endoscopy2022

Safety and efficacy of carbon nanoparticle suspension injection and indocyanine green tracer-guided lymph node dissection during robotic distal gastrectomy in patients with gastric cancer.

Yuan Tian, Yecheng Lin, Honghai Guo, Yiyang Hu, Yong Li, Liqiao Fan, Xuefeng Zhao, Dong Wang, Bibo Tan, Qun Zhao

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 5 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  12. Unexpected black-stained lymph nodes: A case report.International journal of surgery case reports · 2025
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  16. Subserosal Indocyanine Green Plus Submucosal Carbon Nanoparticle Navigated Laparoscopic Gastrectomy (DANCE-01): a Cohort Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yuan Tian *Third Surgery Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yecheng Lin *Third Surgery Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Honghai GuoThird Surgery Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yiyang HuThird Surgery Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yong LiThird Surgery Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Liqiao FanThird Surgery Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Xuefeng ZhaoThird Surgery Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Dong WangThird Surgery Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Bibo TanThird Surgery Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Qun ZhaoThird Surgery Department, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China. zhaoqun@hebmu.edu.cn.ORCID 0000-0003-1603-3002
Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a lack of comparative analyses on the use of carbon nanoparticle suspension injection (CNSI) and indocyanine green (ICG) tracer technology for lymph node detection and their perioperative safety in robotic radical gastrectomy.

methodsA retrospective analysis was performed on patients who underwent robotic distal gastrectomy between November 2019 and November 2020. Patients were assigned to the CNSI group, the ICG group, or the control group. The number of lymph nodes detected, number of lymph nodes detected at each station, number of micro lymph nodes detected, rate of lymph node metastasis, and inoperative and postoperative recovery were compared.

resultsOf the 93 patients analyzed, 34 were in the CNSI group, 27 were in the ICG group, and 32 were in the control group. The mean number of lymph nodes retrieved in the CNSI group (48.44) was higher than that in the ICG (39.19) and control (35.28) groups (P = 0.004; P < 0.001), and there was no difference between the ICG and control groups (P = 0.102). The mean number of micro lymph nodes retrieved in the CNSI group (13.24) was higher than that in the ICG (5.74) and control (5.66) groups (P < 0.001). The lymph node metastasis rates in the CNSI, ICG, and control groups were 5.03, 4.63, and 5.93%, respectively (P > 0.05).

conclusionThe effect of CNSI on lymph node dissection and sorting was better than that of ICG, and CNSI improved the surgical quality and reduced lymph node staging deviation to a greater extent. CNSI was better than ICG in terms of improving the number of micro lymph nodes detected.

Indexed as

NanoparticlesRobotic Surgical ProceduresStomach NeoplasmsCarbonGastrectomyHumansIndocyanine GreenLymphatic MetastasisLymph Node ExcisionLymph NodesRetrospective StudiesCarbonIndocyanine GreenCarbon nanosuspensionIndocyanine greenLymph node dissectionRobotic distal gastrectomy

Identifiers

PMID34254184
PMCPMC9001219
OpenAlexW3181830482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.