ArticleEuropean biophysics journal : EBJ2021
Structure and dynamics of sodium alginate as elucidated by chemical shift anisotropy and site-specific spin-lattice relaxation time measurements.
Article in European biophysics journal : EBJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 14 citations in OpenAlex.
- A low-cost, antimicrobial aloe-alginate hydrogel film containing Australian First Nations remedy 'lemon myrtle oil' (Heliyon · 2024Article
- Analyzing atomic scale structural details and nuclear spin dynamics of four macrolide antibiotics: erythromycin, clarithromycin, azithromycin, and roxithromycin.RSC advances · 2024Article
- Atomic-Scale Resolution Insights into Structural and Dynamic Differences between Ofloxacin and Levofloxacin.ACS omega · 2023Article
- Investigation of the Influence of Various Functional Groups on the Dynamics of Glucocorticoids.ACS omega · 2022Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The biocompatible, biodegradable, linear copolymer sodium alginate is fabricated from [Formula: see text] linked [Formula: see text]-D-mannuronic acid (M block) and [Formula: see text]-L-guluronic acid (G-block). It has wide applications in drug delivery, cell encapsulation, and commercial application in the textile, cosmetics, paper, food, biomedical, and pharmaceutical industries. The structure and dynamics of sodium alginate were here investigated by measuring chemical shift anisotropy (CSA) parameters, spin-lattice relaxation time, and molecular correlation time. The principal components of the CSA tensor were determined by two-dimensional phase-adjusted spinning sideband (2DPASS) cross-polarization magic angle spinning (CP-MAS) SSNMR. The alternating M and G blocks of both equatorial and axial links are associated with greater overall flexibility. The molecular correlation time of the carboxyl carbon of both G and M blocks is faster than for the anomeric carbon and pyranose carbon. This is further experimental evidence of the coexistence of two different dynamics within the polysaccharide chains of sodium alginate, which was previously established by
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