Evidence map›Paper›PMID 34254132›Full record

Observational studyQJM : monthly journal of the Association of Physicians2021

COVID-19-associated mucormycosis presenting to the Emergency Department-an observational study of 70 patients.

A Ramaswami, A K Sahu, A Kumar, S Suresh, A Nair, D Gupta, R Chouhan, R Bhat, R Mathew, J A Majeed and 7 more

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in QJM : monthly journal of the Association of Physicians, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Facial Palsy in Post COVID-19 Invasive Fungal Sinusitis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  7. Article
  8. Article
  9. Observational
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  11. Review
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  16. COVID-19 and Plethora of Fungal Infections.Current fungal infection reports · 2022
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

A RamaswamiDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
A K SahuDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
A KumarDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.ORCID 0000-0002-7976-9765
S SureshDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
A NairDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
D GuptaDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
R ChouhanDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
R BhatDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
R MathewDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
J A MajeedDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
P AggarwalDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
J NayerDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
M EkkaDepartment of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
A ThakarDepartment of Otorhinolaryngology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
G SinghDepartment of Microbiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.ORCID 0000-0002-3169-8419
I XessDepartment of Microbiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
N WigDepartment of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMucormycosis (MM) is a deadly opportunistic fungal infection and a large surge in COVID-19-associated mucormycosis (CAM) is occurring in India.

aimOur aim was to delineate the clinico-epidemiological profile and identify risk factors of CAM patients presenting to the Emergency Department (ED).

designThis was a retrospective, single-centre, observational study.

methodsWe included patients who presented with clinical features or diagnosed MM and who were previously treated for COVID-19 in last 3 months of presentation (recent COVID-19) or currently being treated for COVID-19 (active COVID-19). Information regarding clinical features of CAM, possible risk factors, examination findings, diagnostic workup including imaging and treatment details were collected.

resultsSeventy CAM patients (median age: 44.5 years, 60% males) with active (75.7%) or recent COVID-19 (24.3%) who presented to the ED in between 6 May 2021 and 1 June 2021, were included. A median duration of 20 days (interquartile range: 13.5-25) was present between the onset of COVID-19 symptoms and the onset of CAM symptoms. Ninety-three percent patients had at least one risk factor. Most common risk factors were diabetes mellitus (70%) and steroid use for COVID-19 disease (70%). After clinical, microbiological and radiological workup, final diagnosis of rhino-orbital CAM was made in most patients (68.6%). Systemic antifungals were started in the ED and urgent surgical debridement was planned.

conclusionCOVID-19 infection along with its medical management have increased patient susceptibility to MM.

Indexed as

COVID-19MucormycosisAdultEmergency Service, HospitalFemaleHumansMaleRetrospective StudiesSARS-CoV-2

Identifiers

PMID34254132
PMCPMC8420631
OpenAlexW3180664754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.