ReviewCurrent anesthesiology reports2021
Hypoxemia During One-Lung Ventilation: Does It Really Matter?
Review in Current anesthesiology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06822088 (Effects of Esketamine on Oxygenation and Quality of Recovery in Patients Undergoing Thoracoscopic Surgery), which is not on this map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Esketamine on Oxygenation and Quality of Recovery in Patients Undergoing Thoracoscopic Surgery
Who cites it
21 citing papers in PubMed, 27 citations in OpenAlex.
- Comparison of remimazolam and sevoflurane on arterial oxygenation during one-lung ventilation in thoracoscopic surgery: a randomized controlled trial.Korean journal of anesthesiology · 2025Trial
- Effect of dexmedetomidine on postoperative high-sensitivity cardiac troponin T in patients undergoing video-assisted thoracoscopic surgery: a prospective, randomised controlled trial.BMC pulmonary medicine · 2024Trial
- Effects of positive end-expiratory pressure on regional cerebral oxygen saturation in elderly patients undergoing thoracic surgery during one-lung ventilation: a randomized crossover-controlled trial.BMC pulmonary medicine · 2024Trial
- Aerosolized prostaglandin EClinics (Sao Paulo, Brazil) · 2026Article
- Esketamine versus dexmedetomidine for oxygenation and postoperative quality of recovery in thoracoscopic surgery: a randomized, double-blind, non-inferiority controlled trial.Journal of anesthesia · 2026Article
- Preoperative Inflammatory Ratios and Severe Intraoperative Hypoxemia During One-Lung Ventilation: A Prospective Observational Study.Life (Basel, Switzerland) · 2026Article
- Video double-lumen endotracheal tube reduces hypoxemia during one-lung ventilation in thoracoscopic surgery: a prospective randomized controlled trial.Journal of thoracic disease · 2026Article
- Variation in and deviation from protective ventilation during lung surgery.JTCVS techniques · 2026Article
- Effects of Different Concentrations of Inhaled Oxygen on Lung Collapse and Oxidative Stress in Patients With One Lung Ventilation, a Single-Center Prospective, Double-Blinded, Randomized Controlled Trial.Health science reports · 2025Article
- A Review of Non-Cardiac Complications of General Anesthesia: The Current State of Knowledge.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Mechanical Protective Ventilation: New Paradigms in Thoracic Surgery.Journal of clinical medicine · 2025Review
- Clinical practice of one-lung ventilation in mainland China: a nationwide questionnaire survey.BMC anesthesiology · 2025Article
- Article
- Dexmedetomidine improves lung injury after one-lung ventilation in esophageal cancer patients by inhibiting inflammatory response and oxidative stress.Toxicology research · 2024Article
- The anesthesia management of totally thoracoscopic cardiac surgery: A single-center retrospective study.Heliyon · 2023Article
- Article
- Effects of Ketamine Infusion on Oxygenation in Patients with Chronic Obstructive Pulmonary Disease Undergoing Lung Cancer Surgery.Turkish journal of anaesthesiology and reanimation · 2023Article
- Effects of Acute Hypobaric Hypoxia Exposure on Cardiovascular Function in Unacclimatized Healthy Subjects: A "Rapid Ascent" Hypobaric Chamber Study.International journal of environmental research and public health · 2022Article
- Flurbiprofen used in one-lung ventilation improves intraoperative regional cerebral oxygen saturation and reduces the incidence of postoperative delirium.Frontiers in psychiatry · 2022Article
- The use of oxygen reserve index in one-lung ventilation and its impact on peripheral oxygen saturation, perfusion index and, pleth variability index.BMC anesthesiology · 2021Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewHypoxemia during one-lung ventilation, while decreasing in frequency, persists as an intraoperative challenge for anesthesiologists. Discerning when desaturation and resultant hypoxemia correlates to tissue hypoxia is challenging in the perioperative setting and requires a thorough understanding of the physiology of oxygen delivery and tissue utilization. RECENT
findingsOxygen delivery is not directly correlated with peripheral oxygen saturation in patients undergoing one-lung ventilation, emphasizing the importance of hemoglobin concentration and cardiac output in avoiding tissue hypoxia. While healthy humans can tolerate acute hypoxemia without long-term consequences, there is a paucity of evidence from patients undergoing thoracic surgery. Increasingly recognized is the potential harm of hyperoxic states, particularly in the setting of complex patients with comorbid diseases. SUMMARY: Anesthesiologists are left to determine an acceptable oxygen saturation nadir that is individualized to the patient and procedure based on an understanding of oxygen supply, demand, and the consequences of interventions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.