Evidence map›Paper›PMID 34253788›Full record

ArticleScientific reports2021

Factors associated with achieving intraocular pressure lower than 15 mmHg by Trabectome surgery in primary open-angle glaucoma.

Kentaro Nakamura, Rio Honda, Shoichi Soeda, Norihiro Nagai, Osamu Takahashi, Kazuaki Kadonosono, Yoko Ozawa

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. IOP-lowering and drug-sparing effects of trabectome surgery with or without cyclodialysis ab interno.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kentaro NakamuraDepartment of Ophthalmology, St. Luke's International University and Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan.
Rio HondaDepartment of Ophthalmology, St. Luke's International University and Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan.
Shoichi SoedaDepartment of Ophthalmology, St. Luke's International University and Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan.
Norihiro NagaiDepartment of Ophthalmology, St. Luke's International University and Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan.
Osamu TakahashiGraduate School of Public Health, St. Luke's International University, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan.
Kazuaki KadonosonoDepartment of Ophthalmology and Micro-Technology, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama, Kanagawa, 232-0024, Japan.
Yoko OzawaDepartment of Ophthalmology, St. Luke's International University and Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan. ozaway@luke.ac.jp.ORCID 0000-0003-4797-5705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess good prognostic factors of Trabectome surgery in primary open-angle glaucoma (POAG), clinical records of patients with POAG who underwent Trabectome surgery with/without cataract surgery as the first additive therapy to eye drops between January 2015 and March 2018 were retrospectively reviewed. Overall, data of 79 eyes (79 patients; 50 men; mean age, 68.0 years) up to postoperative 24 months were analyzed. Their mean intraocular pressure (IOP) was 20.4 ± 6.0 mmHg at baseline. Forty-two eyes (53.2%) achieved an IOP < 15 mmHg and ≥ 20% reduction from baseline without additional treatments. Phakic eyes had a better survival probability than pseudophakic eyes after adjusting for age, sex, baseline IOP, best-corrected visual acuity, and eye drop score (hazard ratio 3.096; 95% confidence interval [95% CI] 1.367-7.013; P = 0.007). Phakic eyes treated with combined Trabectome and cataract surgeries (mean survival time, 22.250 months; 95% CI 17.606-26.894) had a better survival probability than pseudophakic eyes treated with Trabectome surgery only (mean survival time, 12.111 months; 95% CI 8.716-15.506; P = 0.009) after the adjustment. Among the eyes treated with Trabectome surgery only, phakic eyes required significantly less additional treatments than pseudophakic eyes (P = 0.04). Trabectome surgery may be indicated for phakic eyes with POAG in addition to eye-drop therapy.

Indexed as

AdultAgedAged, 80 and overFemaleGlaucoma, Open-AngleHumansIntraocular PressureMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesTonometry, OcularTrabeculectomy

Identifiers

PMID34253788
PMCPMC8275622

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.