Evidence map›Paper›PMID 34253742›Full record

ArticleScientific reports2021

Blastocyst formation, embryo transfer and breed comparison in the first reported large scale cloning of camels.

P O Olsson, A H Tinson, N Al Shamsi, K S Kuhad, R Singh, Y B Son, Y Jeong, Y W Jeong, L Cai, K Sakaguchi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Camel biodiversity-and how to conserve it.Animal frontiers : the review magazine of animal agriculture · 2022
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 3 countries.

P O Olsson *UAE Biotech Research Center, 30310 Al Wathba, Abu Dhabi, United Arab Emirates.
A H Tinson *Presidential Camels and Camel Racing Affairs, P.O. Box 17292, Al-Ain, United Arab Emirates.
N Al ShamsiPresidential Camels and Camel Racing Affairs, P.O. Box 17292, Al-Ain, United Arab Emirates.
K S KuhadPresidential Camels and Camel Racing Affairs, P.O. Box 17292, Al-Ain, United Arab Emirates.
R SinghPresidential Camels and Camel Racing Affairs, P.O. Box 17292, Al-Ain, United Arab Emirates.
Y B SonUAE Biotech Research Center, 30310 Al Wathba, Abu Dhabi, United Arab Emirates.
Y JeongUAE Biotech Research Center, 30310 Al Wathba, Abu Dhabi, United Arab Emirates.
Y W JeongUAE Biotech Research Center, 30310 Al Wathba, Abu Dhabi, United Arab Emirates.
L CaiUAE Biotech Research Center, 30310 Al Wathba, Abu Dhabi, United Arab Emirates.
K SakaguchiLaboratory of Theriogenology, Department of Clinical Sciences, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, 060-0818, Japan.
S KimUAE Biotech Research Center, 30310 Al Wathba, Abu Dhabi, United Arab Emirates.
E J ChoiUAE Biotech Research Center, 30310 Al Wathba, Abu Dhabi, United Arab Emirates.
X YuUAE Biotech Research Center, 30310 Al Wathba, Abu Dhabi, United Arab Emirates.
W S HwangUAE Biotech Research Center, 30310 Al Wathba, Abu Dhabi, United Arab Emirates. hwangws@adbrf.org.
Hokkaido University · JPJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cloning, through somatic cell nuclear transfer (SCNT), has the potential for a large expansion of genetically favorable traits in a population in a relatively short term. In the present study we aimed to produce multiple cloned camels from racing, show and dairy exemplars. We compared several parameters including oocyte source, donor cell and breed differences, transfer methods, embryo formation and pregnancy rates and maintenance following SCNT. We successfully achieved 47 pregnancies, 28 births and 19 cloned offspring who are at present healthy and have developed normally. Here we report cloned camels from surgical embryo transfer and correlate blastocyst formation rates with the ability to achieve pregnancies. We found no difference in the parameters affecting production of clones by camel breed, and show clear differences on oocyte source in cloning outcomes. Taken together we demonstrate that large scale cloning of camels is possible and that further improvements can be achieved.

Indexed as

Embryo TransferNuclear Transfer TechniquesAnimalsBlastocystCamelusCloning, OrganismEmbryo Culture TechniquesEmbryo, MammalianEmbryonic DevelopmentFemaleOocytesPregnancyPregnancy RateReproductionUltrasonography

Identifiers

PMID34253742
PMCPMC8275768
OpenAlexW3178096625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.