Evidence map›Paper›PMID 34253677›Full record

ArticleBMJ open2021

Qualitative assessment of the impact of socioeconomic and cultural barriers on uptake and utilisation of tuberculosis diagnostic and treatment tools in East Africa: a cross-sectional study.

Elizabeth F Msoka, Fred Orina, Erica Samson Sanga, Barbara Miheso, Simeon Mwanyonga, Helen Meme, Kiula Kiula, Alphonce Liyoyo, Ivan Mwebaza, Augustus Aturinde and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 5 countries.

Elizabeth F Msoka *Kimanjaro Clinical Research Institute - Kilimanjaro Christian Medical University College, Kilimanjaro Christian Medical Centre, Moshi, United Republic of Tanzania e.fbright@kcri.ac.tz.ORCID 0000-0002-2352-3520
Fred Orina *Centre for Respiratory Diseases Research, Kenya Medical Research Institute, Nairobi, Kenya.
Erica Samson SangaMbeya Medical Research Centre, National Institute for Medical Research (NIMR), Mbeya, United Republic of Tanzania.ORCID 0000-0002-1764-545X
Barbara MihesoCentre for Respiratory Diseases Research, Kenya Medical Research Institute, Nairobi, Kenya.
Simeon MwanyongaMbeya Medical Research Centre, National Institute for Medical Research (NIMR), Mbeya, United Republic of Tanzania.
Helen MemeCentre for Respiratory Diseases Research, Kenya Medical Research Institute, Nairobi, Kenya.
Kiula KiulaKimanjaro Clinical Research Institute - Kilimanjaro Christian Medical University College, Kilimanjaro Christian Medical Centre, Moshi, United Republic of Tanzania.
Alphonce LiyoyoKimanjaro Clinical Research Institute - Kilimanjaro Christian Medical University College, Kilimanjaro Christian Medical Centre, Moshi, United Republic of Tanzania.
Ivan MwebazaDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda.
Augustus AturindeDepartment of Physical Geography and Ecosystem Science, Lund University, Lund, Sweden.
Moses JolobaDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda.
Blandina MmbagaKimanjaro Clinical Research Institute - Kilimanjaro Christian Medical University College, Kilimanjaro Christian Medical Centre, Moshi, United Republic of Tanzania.
Evans AmukoyeCentre for Respiratory Diseases Research, Kenya Medical Research Institute, Nairobi, Kenya.
Nyanda Elias NtinginyaMbeya Medical Research Centre, National Institute for Medical Research (NIMR), Mbeya, United Republic of Tanzania.
Stephen H GillespieDivision of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, Fife, UK.
Wilber SabiitiDivision of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, Fife, UK.
Kenya Medical Research Institute · KEKilimanjaro Christian Medical Centre · TZNational Institute for Medical Research · TZMakerere University · UGUniversity of St Andrews · GBLund University · SEThe University of Dodoma · TZ

Funding

Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda (MITHU)D43TW010319 · FIC · CASE WESTERN RESERVE UNIVERSITY · PI BOOM, W. HENRY, JOLOBA, MOSES LUTAAKOME · 2016 to 2025
$3.1M
FIC NIH HHS D43 TW010319
6 · The paper itself

Abstract

objectivesEarly diagnosis and timely treatment are key elements of a successful healthcare system. We assessed the role of socioeconomic and cultural norms in accelerating or decelerating uptake and utilisation of health technologies into policy and practice.

settingSecondary and tertiary level healthcare facilities (HCFs) in three East African countries. Level of HCF was selected based on the WHO recommendation for implantation of tuberculosis (TB) molecular diagnostics.

participantsUsing implementation of TB diagnostics as a model, we purposively selected participants (TB patients, carers, survivors, healthcare practitioners, community members, opinion leaders and policy-makers) based on their role as stakeholders. In-depth interviews, key informant interviews and focus group discussions were held to collect the data between 2016 and 2018. The data were transcribed, translated, coded and analysed by thematic-content analysis.

resultsA total of 712 individuals participated in the study. Socioeconomic and cultural factors such as poverty, stigma and inadequate knowledge about causes of disease and available remedies, cultural beliefs were associated with low access and utilisation of diagnostic and treatment tools for TB. Poverty made people hesitate to seek formal healthcare resulting in delayed diagnosis and resorting to self-medication and cheap herbal alternatives. Fear of stigma made people hide their sickness and avoid reporting for follow-up treatment visits. Inadequate knowledge and beliefs were fertile ground for aggravated stigma and believing that diseases like TB are caused by spirits and thus cured by spiritual rituals or religious prayers. Cultural norms were also the basis of gender-based imbalance in accessing care, 'I could not go to hospital without my husband's permission', TB survivor.

conclusionOur findings show that socioeconomic and cultural factors are substantial 'roadblocks' to accelerating the uptake and utilisation of diagnostic and treatment tools. Resolving these barriers should be given equal attention as is to health system barriers.

Indexed as

TuberculosisAfrica, EasternCross-Sectional StudiesHumansQualitative ResearchSocial StigmaSocioeconomic Factorsdiagnostic microbiologyhealth policymolecular diagnosticspublic healthtuberculosis

Identifiers

PMID34253677
PMCPMC8276309
OpenAlexW3181438151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.