Evidence map›Paper›PMID 34253675›Full record

ArticleBMJ open2021

Disease burden of diabetes, diabetic retinopathy and their future projections in the UK: cross-sectional analyses of a primary care database.

Sajjad Haider, Rasiah Thayakaran, Anuradha Subramanian, Konstantinos A Toulis, David Moore, Malcolm James Price, Krishnarajah Nirantharakumar

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. A Pragmatic Approach to Improving Management and Patient Flow for Painful Diabetic Neuropathy in UK Primary Care.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sajjad HaiderInstitute Of Applied Health Research, University of Birmingham, Birmingham, UK.ORCID 0000-0001-8111-8577
Rasiah ThayakaranInstitute Of Applied Health Research, University of Birmingham, Birmingham, UK.
Anuradha SubramanianInstitute Of Applied Health Research, University of Birmingham, Birmingham, UK.
Konstantinos A ToulisInstitute Of Applied Health Research, University of Birmingham, Birmingham, UK.
David MooreInstitute Of Applied Health Research, University of Birmingham, Birmingham, UK.
Malcolm James PriceInstitute Of Applied Health Research, University of Birmingham, Birmingham, UK.
Krishnarajah NirantharakumarInstitute Of Applied Health Research, University of Birmingham, Birmingham, UK k.nirantharan@bham.ac.uk.
University of Birmingham · GB

Funding

Medical Research Council MR/S003878/1Medical Research Council MR/W014432/1
6 · The paper itself

Abstract

objectivesTo estimate the current disease burden, trends and future projections for diabetes mellitus (DM) and diabetic retinopathy (DR) in the IQVIA Medical Research Data (IMRD). PARTICIPANTS/DESIGN/

settingWe performed a cross-sectional study of patients aged 12 and above to determine the prevalence of DM and DR from the IMRD database (primary care database) in January 2017, involving a total population of 1 80 824 patients with DM. We also carried out a series of cross-sectional studies to investigate prevalence trends, and then applied a double exponential smoothing model to forecast the future burden of DM and DR in the UK.

resultsThe crude DM prevalence in 2017 was 5.2%. The DR, sight-threatening retinopathy (STR) and diabetic maculopathy prevalence figures in 2017 were 33.78%, 12.28% and 7.86%, respectively, in our IMRD cross-sectional study. There were upward trends in the prevalence of DM, DR and STR, most marked and accelerating in STR in type 1 DM but slowing in type 2 DM, and in the overall prevalence of DR.

conclusionOur results suggest differential rising trends in the prevalence of DM and DR. Preventive strategies, as well as treatment services planning, can be based on these projected prevalence estimates. Improvements that are necessary for the optimisation of care pathways, and preparations to meet demand and capacity challenges, can also be based on this information. The limitations of the study can be overcome by a future collaborative study linking DR screening and hospital eye services data.

Indexed as

Diabetes Mellitus, Type 2Diabetic RetinopathyCost of IllnessCross-Sectional StudiesHumansPrevalencePrimary Health CareRisk FactorsUnited KingdomDiabetic retinopathyEpidemiologyMedical retinaOphthalmology

Identifiers

PMID34253675
PMCPMC8276304
OpenAlexW3181027082

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.