Evidence map›Paper›PMID 34253662›Full record

ArticleBMJ open2021

Decision aids for female BRCA mutation carriers: a scoping review protocol.

Sarah A McGarrigle, Geraldine Prizeman, Carol Spillane, Niamh Byrne, Amanda Drury, David Mockler, Elizabeth M Connolly, Anne-Marie Brady, Yvonne P Hanhauser

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sarah A McGarrigleFaculty of Health Sciences, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0003-4404-6564
Geraldine PrizemanTrinity Centre for Practice and Healthcare Innovation, School of Nursing & Midwifery, Trinity College Dublin, Dublin, Ireland.
Carol SpillaneBreast Care Department, St. James's Hospital, Dublin, Ireland.
Niamh ByrneBreast Care Department, St. James's Hospital, Dublin, Ireland.
Amanda DrurySchool of Nursing, Midwifery and Health Systems, University College Dublin, Dublin, Ireland.ORCID 0000-0002-1720-5673
David MocklerJohn Stearne Library, Trinity College Dublin, Dublin, Ireland.
Elizabeth M ConnollyBreast Care Department, St. James's Hospital, Dublin, Ireland.
Anne-Marie Brady *Trinity Centre for Practice and Healthcare Innovation, School of Nursing & Midwifery, Trinity College Dublin, Dublin, Ireland.
Yvonne P Hanhauser *School of Nursing and Midwifery, Trinity College Dublin, Dublin, Ireland YHanhauser@stjames.ie.
Trinity College Dublin · IESt. James's Hospital · IEUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWomen who inherit a pathogenic mutation in Breast Cancer Susceptibility Genes 1 or 2 (BRCA1 or BRCA2) are at substantially higher risk of developing breast and ovarian cancer than the average woman. Several cancer risk management strategies exist to address this increased risk. Decisions about which risk management strategies to choose are complex, personal and multifactorial for these women. This scoping review will map evidence relevant to cancer risk management decision making in BRCA mutation carriers without a personal history of cancer. The objective is to identify and describe the features of patient decision aids that have been developed for BRCA mutation carriers. This information may be beneficial for designing new decision aids or adapting existing decision aids to support decision making in this population. METHODS AND ANALYSIS: This scoping review will be conducted according to the Joanna Briggs Institute's scoping review methodological framework. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist will be used for guidance. Studies on decision aids for women with a BRCA mutation who are unaffected by breast or ovarian cancer will be considered for inclusion. Five electronic databases will be searched (MEDLINE, EMBASE, Cochrane Library, CINAHL, Web of Science) with no restrictions applied for language or publication date. Studies for inclusion will be selected independently by two review authors. Data will be extracted using a predefined data extraction form. Findings will be presented in tabular form. A narrative description of the evidence will complement the tabulated results. ETHICS AND DISSEMINATION: Ethical approval for conducting this scoping review is not required as this study will involve secondary analysis of existing literature. Findings will be published in a peer-reviewed journal and presented at relevant conferences.

Indexed as

Genes, BRCA2Ovarian NeoplasmsDecision Support TechniquesFemaleGenes, BRCA1HumansMutationResearch DesignScoping Reviews as Topicbreast tumourscancer geneticsgynaecological oncologypreventive medicine

Identifiers

PMID34253662
PMCPMC8276307
OpenAlexW3182551622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.