Evidence map›Paper›PMID 34253517›Full record

ArticleBMJ case reports2021

Congenital cytomegalovirus infection in twin pregnancy.

Ana Araújo Carvalho, Cláudia B Silva, Maria Luísa Martins, Gonçalo Cassiano Santos

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ana Araújo CarvalhoPediatrics Department, Hospital Dona Estefânia, Lisboa, Portugal anacarvalho.fcm@gmail.com.ORCID http://orcid.org/0000-0002-0280-047X
Cláudia B SilvaPediatrics Department, Hospital Dona Estefânia, Lisboa, Portugal.
Maria Luísa MartinsObstetrics Department, Prenatal Diagnosis Center, Maternidade Doutor Alfredo da Costa, Lisboa, Portugal.
Gonçalo Cassiano SantosNeonatal Intensive Care Unit, Maternidade Doutor Alfredo da Costa, Lisboa, Portugal.
Hospital de Dona Estefânia · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) infection is one of the preeminent congenital viral infections, and despite its potential morbidity, uncertainty about its physiopathology, prevention and treatment remains until now. We report a case of a dichorionic and diamniotic twin pregnancy in which only one of the fetus had signs of being affected. The first twin had prenatal diagnosis of intrauterine growth restriction and hyperechogenic bowel, attributable to CMV infection, while there was no evidence of infection of the second one. Prenatal treatment was done with maternal administration of valacyclovir and postnatal treatment of the infected newborn with oral valganciclovir with normal neurodevelopment assessment at 12 months corrected age. In this case, maternal CMV infection was not equally transmitted to both fetuses, suggesting that there may be intrinsic fetal and placental factors influencing both transmission and the clinical features of the infection.

Indexed as

Cytomegalovirus InfectionsPregnancy Complications, InfectiousFemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalPlacentaPregnancyPregnancy, Twincongenital disordersinfectious diseasesmaterno-fetal medicine

Identifiers

PMID34253517
PMCPMC8276144
OpenAlexW3181204534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.