Evidence map›Paper›PMID 34253410›Full record

ArticleIndian journal of medical microbiology

Seroprevalence of SARS-CoV-2 specific IgG antibodies among eye care workers in South India.

Rajapandian Siva Ganesa Karthikeyan, Gunasekaran Rameshkumar, Chidambaranathan Gowri Priya, Prajna Lalitha, Ramamoorthi Devi, Mani Iswarya, Ravilla D Ravindran

Open access · goldAbstract read
In one paragraph

Article in Indian journal of medical microbiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Seroprevalence of IgG antibodies against SARS-CoV-2 in India, March 2020 to August 2021: a systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rajapandian Siva Ganesa KarthikeyanDepartment of Ocular Microbiology, Aravind Eye Hospital, Madurai, India. Electronic address: siva.ganesa.k@aravind.org.
Gunasekaran RameshkumarDepartment of Ocular Microbiology, Aravind Eye Hospital, Madurai, India.
Chidambaranathan Gowri PriyaDepartment of Immunology and Stem Cell Biology, Aravind Medical Research Foundation, Madurai, India.
Prajna LalithaDepartment of Ocular Microbiology, Aravind Eye Hospital, Madurai, India.
Ramamoorthi DeviDepartment of Biostatistics, Aravind Eye Hospital, Madurai, India.
Mani IswaryaDepartment of Biostatistics, Aravind Eye Hospital, Madurai, India.
Ravilla D RavindranAravind Eye Care System, Madurai, India.
Aravind Eye Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHealth care workers are at higher risk of acquiring the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. This study aims to understand the seroprevalence of anti-SARS-CoV-2 IgG antibody among the eye care workers in South India.

methodsThe participants included eye care workers from the nine eye care centres. All the participants were interviewed with a questionnaire to obtain essential information about socio-demographics, past contact with COVID-19 patients and additional information as recommended by Indian Council of Medical Research, India. Serum samples were tested for anti-SARS-CoV-2 IgG antibodies by ELISA.

resultsA total of 1313 workers were included and 207 (15.8%) were positive for the SARS-CoV-2 IgG antibody. The seropositivity was higher in the moderate risk group (19.5%) followed by low (18.6%) and high risk (13.7%) groups. The seropositivity was significantly higher among i) day scholars compared to hostellers (OR - 2.22, 1.56 to 3.15, P ​< ​0.0001), ii) individuals with history of flu-like illness (4.57, 3.08-6.78, P ​< ​0.001) or who were symptomatic or in contact with COVID 19 positive cases (2.2, 1.02-4.75, P - 0.043) and iii) individuals with history of systemic illness (2.11, 1.39-3.21, P ​< ​0.001). Individuals (11.97%) who had no history of contact or any illness were also seropositive.

conclusionsThe effectiveness of the protective measures taken against COVID infection was evident from the lower percentage of seropositivity in the high risk group. The study highlighted the need to create awareness among individuals to follow strict safety measures even in non-work hours and also in social circles.

Indexed as

COVID-19Health PersonnelAntibodies, ViralHumansImmunoglobulin GIndiaOphthalmologyOptometrySARS-CoV-2Seroepidemiologic StudiesAntibodies, ViralImmunoglobulin GELISAEye care workersHealth care workersIgG antibodySARS-CoV-2Seroprevalence

Identifiers

PMID34253410
PMCPMC8270789
OpenAlexW3180977777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.