Evidence map›Paper›PMID 34253111›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2022

Accuracy and Reliability of 4D-CT and Flexible Laryngoscopy in Upper Airway Evaluation in Robin Sequence.

Austin S Lam, Michael D Bindschadler, Kelly N Evans, Seth D Friedman, Matthew S Blessing, Randall Bly, Michael L Cunningham, Mark A Egbert, Russell E Ettinger, Emily R Gallagher and 11 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 1 country.

Austin S LamDivision of Pediatric Otolaryngology, Seattle Children's Hospital, Seattle, Washington, USA.
Michael D BindschadlerDepartment of Radiology, University of Washington School of Medicine, Seattle, Washington, USA.
Kelly N EvansDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.
Seth D FriedmanDepartment of Radiology, University of Washington School of Medicine, Seattle, Washington, USA.
Matthew S BlessingDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.
Randall BlyDivision of Pediatric Otolaryngology, Seattle Children's Hospital, Seattle, Washington, USA.
Michael L CunninghamDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.
Mark A EgbertCraniofacial Center, Seattle Children's Hospital, Seattle, Washington, USA.
Russell E EttingerCraniofacial Center, Seattle Children's Hospital, Seattle, Washington, USA.
Emily R GallagherDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.
Richard A HopperCraniofacial Center, Seattle Children's Hospital, Seattle, Washington, USA.
Kaalan JohnsonDivision of Pediatric Otolaryngology, Seattle Children's Hospital, Seattle, Washington, USA.
Jonathan A PerkinsDivision of Pediatric Otolaryngology, Seattle Children's Hospital, Seattle, Washington, USA.
Erin K RombergDepartment of Radiology, University of Washington School of Medicine, Seattle, Washington, USA.
Kathleen C Y SieDivision of Pediatric Otolaryngology, Seattle Children's Hospital, Seattle, Washington, USA.
Srinivas M SusarlaCraniofacial Center, Seattle Children's Hospital, Seattle, Washington, USA.
Carlton J ZdanskiDepartment of Otolaryngology/Head & Neck Surgery and Pediatrics, University of North Carolina, Chapel Hill, North Carolina, USA.
Xing WangBiostatistics, Epidemiology and Analytics in Research (BEAR) Core, Seattle Children's Research Institute, Seattle, Washington, USA.
Jeffrey P OtjenDepartment of Radiology, University of Washington School of Medicine, Seattle, Washington, USA.
Francisco A PerezDepartment of Radiology, University of Washington School of Medicine, Seattle, Washington, USA.
John P DahlDivision of Pediatric Otolaryngology, Seattle Children's Hospital, Seattle, Washington, USA.
Seattle Children's Hospital · USUniversity of Washington · USUniversity of North Carolina at Chapel Hill · US

Funding

Research Training in OtolaryngologyT32DC000018 · NIDCD · UNIVERSITY OF WASHINGTON · PI STONE, JENNIFER S. · 1989 to 2023
$7.8M
NIDCD NIH HHS T32 DC000018
6 · The paper itself

Abstract

objectivesTo evaluate the performance of 4-dimensional computed tomography (4D-CT) in assessing upper airway obstruction (UAO) in patients with Robin sequence (RS) and compare the accuracy and reliability of 4D-CT and flexible fiber-optic laryngoscopy (FFL). STUDY

designProspective survey of retrospective clinical data.

settingSingle, tertiary care pediatric hospital.

methodsAt initial and 30-day time points, a multidisciplinary group of 11 clinicians who treat RS rated UAO severity in 32 sets of 4D-CT visualizations and FFL videos (dynamic modalities) and static CT images. Raters assessed UAO at the velopharynx and oropharynx (1 =

resultsThere was similar intrarater agreement (moderate to substantial) with 4D-CT and FFL, and both demonstrated fair interrater agreement. Both modalities underestimated UAO severity, although 4D-CT ratings were significantly more accurate, as determined by QPC similarity, than FFL (-1.06 and -1.46 vs QPC ratings,

conclusionAlthough 4D-CT may be more accurate in assessing the degree of UAO in patients with RS, 4D-CT and FFL assessments demonstrate similar reliability. Additionally, 4D-CT may be interpreted with greater confidence by nonotolaryngologists who care for these patients.

Indexed as

LaryngoscopyPierre Robin SyndromeChildFour-Dimensional Computed TomographyHumansProspective StudiesReproducibility of ResultsRetrospective Studies4D-CTcomputed tomographyflexible fiber-optic laryngoscopyRobin sequenceupper airway obstruction

Identifiers

PMID34253111
PMCPMC8755858
OpenAlexW3182954500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.