Evidence map›Paper›PMID 34253106›Full record

ArticleWomen's health (London, England)

The biobehavioral impacts of sexual violence: Findings from an acute repeat survivor of vaginal rape.

Katherine M Anderson, Mimi Ghosh, Maile Y Karris, Eleanor Capozzi, Douglas A Granger, Jamila K Stockman

Open access · goldAbstract read
In one paragraph

Article in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Katherine M AndersonDivision of Infectious Diseases and Global Public Health, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0001-9675-3653
Mimi GhoshDepartment of Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, DC, USA.
Maile Y KarrisDivision of Infectious Diseases and Global Public Health, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA, USA.
Eleanor CapozziDepartment of Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, DC, USA.
Douglas A GrangerInstitute for Interdisciplinary Salivary Bioscience Research, University of California Irvine, Irvine, CA, USA.
Jamila K StockmanDivision of Infectious Diseases and Global Public Health, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA, USA.
Milken Institute · USUniversity of California San Diego · USEmory University · USJohns Hopkins University · US

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Mitchell Smith · 1994 to 2026
$78.4M
SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Italo Mocchetti · 2015 to 2026
$29.6M
Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid, ELAINE WETHINGTON · 2003 to 2026
$15.2M
Sexual trauma and HIV susceptibility among women: the role of stress and genital immunityR01AI128803 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GHOSH, MIMI, STOCKMAN, JAMILA KINSHASA · 2017 to 2020
$2.4M
NIAID NIH HHS P30 AI036214NIAID NIH HHS P30 AI117970NIAID NIH HHS R01 AI128803NIA NIH HHS P30 AG022845
6 · The paper itself

Abstract

backgroundIndividuals who have experienced repeat sexual violence victimization face adverse mental and physical health outcomes, including immune and stress response functioning. We aim to further understand repeat sexual violence victimization to develop responsive and appropriate treatment for survivors of sexual violence.

methodsWe present the immunological and contextual findings of a participant (

resultsThe case study participant, aged 18 years upon enrollment, experienced sexual trauma before four of five study visits. Trends in the mental health indicators demonstrate reciprocal fluctuations in adverse mental health and resilience in accordance with revictimization and circumstantial changes. Suppressed immune biomarkers appear to correlate with increased adverse mental health, while mental health recovery trends with immunological recovery. The participant presents with dysregulated hypothalamic-pituitary-adrenal axis diurnal profile.

conclusionsThis profile illustrates the intra-individual biobehavioral impact of experience with revictimization over the course of 6 months, capturing experiences that are rarely studied either longitudinally or with the depth of the current research. The findings underscore the value of monitoring cervicovaginal immune functioning and hypothalamic-pituitary-adrenal axis dysregulation in coordination with changes in mental health over the course of repeated sexual trauma.

Indexed as

RapeSex OffensesCase-Control StudiesFemaleHumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemPregnancySurvivorsfemale genital tractimmunologymental healthsexual violence

Identifiers

PMID34253106
PMCPMC8280840
OpenAlexW3177507185

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.