Evidence map›Paper›PMID 34253065›Full record

ArticlemBio2021

Glycan-Dependent Corneocyte Adherence of Staphylococcus epidermidis Mediated by the Lectin Subdomain of Aap.

Paroma Roy, Alexander R Horswill, Paul D Fey

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Case Report: Beyond commensal:Frontiers in pediatrics · 2026
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  4. Microbiology (Reading, England) · 2025
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  5. Review
  6. Polymicrobial interactions betweenbioRxiv : the preprint server for biology · 2024
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  7. Article
  8. Article
  9. bioRxiv : the preprint server for biology · 2023
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  11. Biomolecular NMR assignments · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Paroma RoyDepartment of Pathology and Microbiology, University of Nebraska Medical Centergrid.266813.8, Omaha, Nebraska, USA.
Alexander R HorswillDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Paul D FeyDepartment of Pathology and Microbiology, University of Nebraska Medical Centergrid.266813.8, Omaha, Nebraska, USA.
University of Nebraska Medical Center · USUniversity of Colorado Denver · US

Funding

The S. aureus biofilm lifecycleP01AI083211 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KIELIAN, TAMMY L · 2009 to 2023
$32.1M
Quorum sensing, diversity and skin inflammationR01AI153185 · NIAID · UNIVERSITY OF COLORADO DENVER · PI GALLO, RICHARD L, HORSWILL, ALEXANDER R · 2020 to 2024
$3.2M
NIAID NIH HHS P01 AI083211NIAID NIH HHS R01 AI153185
6 · The paper itself

Abstract

Staphylococcus epidermidis and other coagulase-negative staphylococci (CoNS) that colonize skin are known to promote skin immunity and inhibit colonization of pathogens that cause skin and soft tissue infections, including Staphylococcus aureus. However, S. epidermidis adherence to corneocytes, the cells that constitute the uppermost layer of the skin epidermis, remains poorly understood. Our study documents that S. epidermidis corneocyte adherence is dependent upon the

Indexed as

Adhesins, BacterialBacterial AdhesionBacterial ProteinsLectinsPolysaccharidesSkinStaphylococcal InfectionsStaphylococcus epidermidisAdhesins, BacterialBacterial ProteinsLectinsPolysaccharidesaccumulation-associated proteinskin adherenceStaphylococcus aureusStaphylococcus epidermidis

Identifiers

PMID34253065
PMCPMC8406310
OpenAlexW3178000751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.