Evidence map›Paper›PMID 34253063›Full record

ArticlemBio2021

Protein Transfer through an F Plasmid-Encoded Type IV Secretion System Suppresses the Mating-Induced SOS Response.

Abu Amar M Al Mamun, Kouhei Kishida, Peter J Christie

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Conjugative delivery of toxin genesJournal of bacteriology · 2025
    Article
  7. The extended mobility of plasmids.Nucleic acids research · 2025
    Review
  8. The metabolic burden associated with plasmid acquisition: An assessment of the unrecognized benefits to host cells.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Ligand-DisplayingbioRxiv : the preprint server for biology · 2023
    Article
  19. Article
  20. Host-specific plasmid evolution explains the variable spread of clinical antibiotic-resistance plasmids.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abu Amar M Al MamunDepartment of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.
Kouhei KishidaDepartment of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.
Peter J ChristieDepartment of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.

Funding

TRANSLOCATION OF DNA ACROSS THE AGROBACTERIUM ENVELOPER01GM048746 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CHRISTIE, PETER J. · 1998 to 2018
$6.9M
Biological And Structural Diversity Of Bacterial Type IV Secretion SystemsR35GM131892 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI PETER j. CHRISTIE · 2019 to 2026
$3.8M
Mitigation of Stress Responses By Protein Transfer Through Conjugation MachinesR21AI159970 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CHRISTIE, PETER J. · 2021 to 2022
$429k
NIAID NIH HHS R21 AI159970NIGMS NIH HHS R01 GM048746NIGMS NIH HHS R35 GM131892
6 · The paper itself

Abstract

Bacterial type IV secretion systems (T4SSs) mediate the conjugative transfer of mobile genetic elements (MGEs) and their cargoes of antibiotic resistance and virulence genes. Here, we report that the pED208-encoded T4SS (Tra

Indexed as

Conjugation, GeneticSOS Response, GeneticsBacterial ProteinsDNA, BacterialEscherichia coliF FactorPlasmidsTranslocation, GeneticType IV Secretion SystemsBacterial ProteinsDNA, BacterialType IV Secretion Systemsconjugationmutationprotein translocationSOS responsestress responsetype IV secretion

Identifiers

PMID34253063
PMCPMC8406263
OpenAlexW3179598697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.