Evidence map›Paper›PMID 34252844›Full record

ArticleEarly human development2021

Maternal verbal scaffolding: association with higher language skills for 20-month-old children with prenatal polysubstance exposure.

Jean R Lowe, Lauren Hund, Dominique E Rodriguez, Asma Qamruddin, Lawrence Leeman, Julia M Stephen, Ludmila N Bakhireva

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Early human development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jean R LoweDepartment of Pediatrics, University of New Mexico, Albuquerque, NM, USA. Electronic address: JLowe@salud.unm.edu.
Lauren HundSchool of Law, University of New Mexico, Albuquerque, NM, USA.
Dominique E RodriguezSubstance Use Research and Education (SURE) Center, University of New Mexico College of Pharmacy, Albuquerque, NM, USA.
Asma QamruddinAdvocate Lutheran Children's Hospital, Chicago, IL, USA.
Lawrence LeemanDepartment of Family and Community Medicine, University of New Mexico, Albuquerque, NM, USA; Department of Obstetrics and Gynecology, University of New Mexico, Albuquerque, NM, USA.
Julia M StephenThe Mind Research Network a division of Lovelace Biomedical Research Institute, Albuquerque, NM, USA.
Ludmila N BakhirevaSubstance Use Research and Education (SURE) Center, University of New Mexico College of Pharmacy, Albuquerque, NM, USA; Department of Family and Community Medicine, University of New Mexico, Albuquerque, NM, USA; Division of Epidemiology, Biostatistics, and Preventive Medicine, Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.
University of New Mexico · USBiomedical Research Institute · US

Funding

The effect of the COVID-19 pandemic on alcohol use and psycho-somatic health in pregnant and postpartum women with intersecting vulnerabilities.R01AA021771 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BAKHIREVA, LUDMILA NICOLE · 2013 to 2022
$6.5M
6/6 Planning for the HEALthy Early Development StudyR34DA050237 · NIDA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BAKHIREVA, LUDMILA NICOLE, LEEMAN, LAWRENCE M · 2019 to 2019
$542k
NIAAA NIH HHS R01 AA021771NIDA NIH HHS R34 DA050237
6 · The paper itself

Abstract

backgroundThe number of children with prenatal polysubstance exposure is increasing. Supportive mother-child interaction is a protective factor, which can ameliorate adverse effects of prenatal polysubstance exposure on developmental outcomes.

aimTo examine the role of maternal verbal scaffolding on cognitive and language development in children with prenatal polysubstance exposure. STUDY

designPregnant women were recruited, and we prospectively followed mother-child dyads to 20 months of age. This analysis included 66 dyads (33 healthy controls and 33 with prenatal polysubstance exposure). Multivariable linear regression modelling was used to examine the cross-sectional association between maternal scaffolding and Bayley Scales of Infant and Toddler Development (BSID-III) score, as well as an interaction between the study group and scaffolding score. OUTCOME MEASURES: The BSID-III cognitive and language score was used. Videotaped mother-child play was coded to obtain a maternal verbal scaffolding score. Effect sizes were measured using average differences in scores between groups.

resultsThere was no evidence of an association between study group and maternal scaffolding scores. Children in the polysubstance exposure group had lower cognitive and language scores compared to controls, but this association was not statistically significant after controlling for maternal education. Maternal scaffolding was predictive of language scores, with scores increasing by 1.24 points on average (95% CI: 0.42, 2.06) for every 1-point increase in scaffolding score after adjustment for covariates. There was no evidence of a study group-by-scaffolding interaction with respect to the language or cognitive scores.

conclusionsMaternal scaffolding during play was associated with language development in children with and without prenatal polysubstance exposure.

Indexed as

Language DevelopmentMother-Child RelationsCognitionCross-Sectional StudiesFemaleHumansInfantPregnancyPregnant PeopleLanguage developmentMaternal verbal scaffoldingMother-child interactionsPrenatal polysubstance exposureSubstance use

Identifiers

PMID34252844
PMCPMC9084305
OpenAlexW3180925126

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.