Evidence map›Paper›PMID 34252830›Full record

ArticleEpilepsy & behavior : E&B2021

Patients with epilepsy during the COVID-19 pandemic: Depressive symptoms and their association with healthcare access.

Mariana Dos Santos Lunardi, Rachel Marin de Carvalho, Raquel Alencastro Veiga Domingues Carneiro, Felipe Giacomini, Kette D Valente, Katia Lin

Open access · bronzeAbstract read
In one paragraph

Article in Epilepsy & behavior : E&B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Seizure control during the COVID-19 pandemic: Correlating Responsive Neurostimulation System data with patient reports.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mariana Dos Santos LunardiMedical Sciences Graduate Program, Federal University of Santa Catarina (UFSC), Florianópolis, SC, Brazil. Electronic address: marianalunardi1408@gmail.com.
Rachel Marin de CarvalhoResearcher from Coordination for the Improvement of Higher Education Personnel (CAPES), São Paulo, SP, Brazil.
Raquel Alencastro Veiga Domingues CarneiroNeurology Division, Federal University of Santa Catarina (UFSC), Florianópolis, SC, Brazil.
Felipe GiacominiNeurology Division, Federal University of Santa Catarina (UFSC), Florianópolis, SC, Brazil.
Kette D ValentePsychiatry Department, Clinic's Hospital University of Sao Paulo Medical School (HCFMUSP), Sao Paulo, SP, Brazil.
Katia LinMedical Sciences Graduate Program, Federal University of Santa Catarina (UFSC), Florianópolis, SC, Brazil; Neurology Division, Federal University of Santa Catarina (UFSC), Florianópolis, SC, Brazil.
Universidade Federal de Santa Catarina · BRCoordenação de Aperfeicoamento de Pessoal de Nível Superior · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe coronavirus disease 2019 (COVID-19) outbreak impacted the lives of worldwide people with epilepsy (PWE) in various aspects, particularly in those countries most significantly affected by this pandemic, such as Brazil. We aimed to investigate the prevalence of depressive symptoms in PWE and their correlation with epilepsy features and access to treatment.

methodsPWE were invited to answer a cross-sectional online-based survey to assess and rate depressive symptoms using the NDDI-E during the first year of the COVID-19 pandemic and its relation to multiple lifestyles epilepsy clinical aspects.

resultsA total of 490 PWE were recruited. The prevalence of depressive symptoms during the COVID-19 pandemic was 35.3% (cutoff score > 15 on NDDI-E). The factors associated with higher NDDI-E scores were: female sex, increased seizure frequency, barriers to access to their treating physician and antiseizure medication, and unemployment. Regarding the pandemic impact on PWE healthcare, 29.2% reported restricted access to their medication, 46.1% barriers to access their physicians, 94.2% had their consultations canceled due to the pandemic, and 28.4% had seizure worsening in this period.

conclusionThe COVID-19 pandemic affected PWE access to the healthcare system. Depressive symptoms were more severe in patients with higher seizure frequency who had difficulties obtaining proper medical care. The COVID-19 pandemic may impact the healthcare and mental wellbeing of patients with chronic diseases such as epilepsy. Nevertheless, prospective studies on epilepsy and COVID-19 are still lacking.

Indexed as

COVID-19EpilepsyCross-Sectional StudiesDepressionFemaleHealth Services AccessibilityHumansPandemicsProspective StudiesSARS-CoV-2Antiseizure medicationCOVID-19DepressionEpilepsyHealthcare

Identifiers

PMID34252830
PMCPMC8412878
OpenAlexW3178216329

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.