Evidence map›Paper›PMID 34252306›Full record

ArticleAntimicrobial agents and chemotherapy2021

Endodontic Infections and the Extent of Antibiotic Overprescription among Italian Dental Practitioners.

Francesca Licata, Gianfranco Di Gennaro, Vincenza Cautela, Carmelo Giuseppe Angelo Nobile, Aida Bianco

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 18 citations in OpenAlex.

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  13. How decisions are made: Antibiotic stewardship in dentistry.Infection control and hospital epidemiology · 2023
    Article
  14. Article
  15. Antibiotics in Dentistry: A Narrative Review of the Evidence beyond the Myth.International journal of environmental research and public health · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Francesca LicataDepartment of Health Sciences, School of Medicine, University of Catanzaro Magna Græcia, Catanzaro, Italy.
Gianfranco Di GennaroDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabriagrid.7778.f, Cosenza, Italy.
Vincenza CautelaDepartment of Health Sciences, School of Medicine, University of Catanzaro Magna Græcia, Catanzaro, Italy.
Carmelo Giuseppe Angelo NobileDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabriagrid.7778.f, Cosenza, Italy.
Aida BiancoDepartment of Health Sciences, School of Medicine, University of Catanzaro Magna Græcia, Catanzaro, Italy.ORCID 0000-0003-4674-0306
Magna Graecia University · ITUniversity of Calabria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objectives of this study were to evaluate the pattern of antibiotic prescription for endodontic infections (EIs) among Italian dental practitioners (DPs) and to explore the role of potential predictors of antibiotic overprescription. A nationwide cross-sectional survey was conducted between 1 April and 30 October 2019 using a structured questionnaire. Information was gathered on demographics, professional characteristics, and practices regarding antibiotic prescription for both therapeutic and prophylactic purposes. Of the 1,250 invited DPs, 563 answered the general questionnaire (response rate of 52.6%). The proportions of DPs who prescribed an antibiotic without indication for therapeutic and prophylactic purposes were 33.3% and 30.2%, respectively. Acute alveolar abscess without systemic involvement represents the clinical scenario at a high risk of overprescription for therapeutic purposes. Possible predictors of overprescribing included demographics and professional characteristics. Moreover, overprescribing was found to be higher for EIs without an indication than for the cases in which the prescription is indicated for therapeutic purposes. The odds of overprescription for prophylactic purposes were higher for cases of acute apical periodontitis and lower for cases of symptomatic irreversible pulpitis than for acute and chronic alveolar abscesses, for which prescription is indicated. The main findings of the present study provide up-to-date insight into the pattern of antibiotic prescriptions for EIs and evidence useful to identify opportunities to reduce overprescription among DPs through tailored interventions. The development of practical antibiotic prescribing guidelines with a clear description of indications and regimen ease of use is strongly needed.

Indexed as

Anti-Bacterial AgentsPractice Patterns, Dentists'Cross-Sectional StudiesDentistsHumansItalyProfessional RoleAnti-Bacterial Agentsantibiotic prescriptionantimicrobial resistanceappropriatenessdental practitionersdentistryItaly

Identifiers

PMID34252306
PMCPMC8448121
OpenAlexW3181965553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.