ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2021
Cardiometabolic Risk Trajectory Among Older Americans: Findings From the Health and Retirement Study.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Differences in phenotypic and functional aging trajectories among people aging with disability and the US general population.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Spouses' Individual and Shared Cumulative Risk: Implications for Functional Health and Longevity in Older Adulthood.American journal of preventive medicine · 2025Article
- The Association Between Cardiometabolic Risk and Cognitive Function Among Older Americans and Chinese.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Dried blood spot based biomarkers in the Health and Retirement Study: 2006 to 2016.American journal of human biology : the official journal of the Human Biology Council · 2024Article
- Geroscience and pathology: a new frontier in understanding age-related diseases.Pathology oncology research : POR · 2024Review
- Older Adults in the United States Have Worse Cardiometabolic Health Compared to England.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundCardiometabolic risk (CMR) is a key indicator of physiological decline with age, but age-related declines in a nationally representative older US population have not been previously examined.
methodsWe examined the trajectory of CMR over 8 years of aging, from 2006/2008 to 2014/2016, among 3528 people older than age 50 in the Health and Retirement Study. We used growth curve models to examine change in total CMR as well as in individual cardiometabolic biomarkers to understand how baseline differences and rates of change vary across sociodemographic characteristics, by smoking status, and medication use.
resultsTotal CMR did not change among respondents who survived over 8 years. Despite significant differences in CMR across demographic and education groups at baseline, the pace of change with age did not differ by these characteristics. Among individual biomarkers, risk levels of diastolic blood pressure, resting heart rate, and total cholesterol decreased over 8 years while glycosylated hemoglobin, waist circumference, and pulse pressure increased over that time. Both the statistical significance levels and the magnitudes of the reduction over time with age in diastolic blood pressure, resting heart rate, and total cholesterol in models adjusted for age, race/ethnicity, gender, smoking, and education were reduced after controlling for blood pressure and cholesterol medication.
conclusionsThe relatively constant total CMR level over 8 years occurred because some indicators improved with age while some deteriorated in this period. Medication use contributed to the improvement in blood pressure, resting heart rate, and total cholesterol.
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Registered trials
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