Evidence map›Paper›PMID 34252129›Full record

ArticlePloS one2021

Evaluation of a community-based HIV test and start program in a conflict affected rural area of Yambio County, South Sudan.

Cecilia Ferreyra, Laura Moretó-Planas, Fara Wagbo Temessadouno, Beatriz Alonso, Buai Tut, Victoria Achut, Mohamed Eltom, Endashaw M Aderie, Vicente Descalzo-Jorro

Erratum issuedOpen access · goldAbstract readEvaluation Study
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Cecilia FerreyraMédecins sans Frontières, Barcelona, Spain.ORCID 0000-0001-5480-7940
Laura Moretó-PlanasMédecins sans Frontières, Barcelona, Spain.
Fara Wagbo TemessadounoMédecins sans Frontières, Barcelona, Spain.
Beatriz AlonsoMédecins sans Frontières, Juba, South Sudan.
Buai TutMédecins sans Frontières, Juba, South Sudan.
Victoria AchutMinistry of Health, Republic of South Sudan, HIV/AIDS/STI, Juba, South Sudan.
Mohamed EltomMédecins sans Frontières, Nairobi, Kenya.
Endashaw M AderieMédecins sans Frontières, Juba, South Sudan.
Vicente Descalzo-JorroMédecins sans Frontières, Juba, South Sudan.
Médecins Sans Frontières · ESFederal Ministry of Health · SDVétérinaires Sans Frontières Suisse · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntiretroviral therapy (ART) coverage in South Sudan is around 10%. Access to HIV care in settings with low ART coverage or conflict affected is still low; innovative strategies are needed to increase access and ensure continuation of ART during instability. A pilot HIV test and start project was implemented in a conflict-affected area of South Sudan. In a retrospective analysis, we determined the feasibility and outcomes of this intervention.

methodsProgramme data from July 2015 to June 2018 was analysed. The project involved five mobile teams offering HIV counselling and testing (HCT) and same day ART initiation at community level. Baseline and follow-up information on clinical, immunological and viral load (VL) was routinely recorded, as well as treatment outcomes. A semi-qualitative study was conducted to assess acceptability of the program among beneficiaries and community members.

resultsBy June 2018, 14824 people received counselling and testing for HIV and 498 (3.4%) tested positive. Out of those 395 (79.3%) started ART. A total of 72 ART patients were organized in 26 Community ART Groups (CAGs) and contingency plan was activated 9 times for 101 patients. Kaplan-Meier estimated retention in care (RIC) at 12 and 18 months was 80.6% [95% CI: 75.9-84.5%] and 69.9% [95% CI: 64.4-74.8%] respectively. RIC was significantly higher at 18 months in patients under community ART groups (CAGs) (90.9% versus 63.4% p<0.001) when compared to patients on regular follow up. VL suppression at 12 months was 90.3% and overall virological suppression reached 91.2%. A total of 279 persons were interviewed about the MSF program perception and acceptance: 98% had heard about the programme and 84% found it beneficial for the community, 98% accepted to be tested and only 4% found disadvantages to the programme.

conclusionsOur study shows that HCT and early ART initiation in conflict affected populations can be provided with good program outcomes. RIC and virological suppression are comparable with facility-based HIV programs and to those in stable contexts. This model could be extrapolated to other similar contexts with low access to ART and where security situation is a concern.

Indexed as

Armed ConflictsHIV TestingResidence CharacteristicsRural PopulationAdultAnti-HIV AgentsCD4 Lymphocyte CountCounselingFemaleFollow-Up StudiesHIV InfectionsHumansKaplan-Meier EstimateMaleMiddle AgedPatient Acceptance of Health CareAnti-HIV Agents

Identifiers

PMID34252129
PMCPMC8274874
OpenAlexW3177624641

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.