Evidence map›Paper›PMID 34252035›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Protein Kinase C-Mediated Phosphorylation and α2δ-1 Interdependently Regulate NMDA Receptor Trafficking and Activity.

Meng-Hua Zhou, Shao-Rui Chen, Li Wang, Yuying Huang, Meichun Deng, Jixiang Zhang, Jiyuan Zhang, Hong Chen, Jiusheng Yan, Hui-Lin Pan

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. HIV-1 gp120 Induces Nociceptive Hypersensitivity via α2δ-1-Bound NMDA Receptors at Primary Afferent→Excitatory Neuron Synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  10. GαScience signaling · 2025
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  18. Review
  19. Article
  20. Calcineurin and CK2 Reciprocally Regulate Synaptic AMPA Receptor Phenotypes via α2δ-1 in Spinal Excitatory Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Meng-Hua ZhouDepartment of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Shao-Rui ChenDepartment of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Li WangDepartment of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Yuying HuangDepartment of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Meichun DengDepartment of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Jixiang ZhangDepartment of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030.ORCID https://orcid.org/0000-0002-1641-8650
Jiyuan ZhangDepartment of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Hong ChenDepartment of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Jiusheng YanDepartment of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030.
Hui-Lin PanDepartment of Anesthesiology and Perioperative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030 huilinpan@mdanderson.org.ORCID https://orcid.org/0000-0001-8444-3770
The University of Texas MD Anderson Cancer Center · US

Funding

Molecular Determinants of Synaptic Plasticity in Chronic PainR01NS101880 · NINDS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Shao-Rui Chen, Hui-Lin Pan · 2017 to 2026
$4.1M
Signaling Mechanisms of Opioid-Induced Hyperalgesia and ToleranceR01DA041711 · NIDA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Shao-Rui Chen, Hui-Lin Pan · 2017 to 2026
$3.8M
Mechanisms of Neuronal Plasticity in Neuropathic PainR01GM120844 · NIGMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI PAN, HUI-LIN · 2016 to 2019
$1.6M
NIDA NIH HHS R01 DA041711NIGMS NIH HHS R01 GM120844NINDS NIH HHS R01 NS101880
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCalcium Channels, L-TypeFemaleHEK293 CellsHumansMaleMiceMice, Inbred C57BLNeuronal PlasticityPhosphorylationProtein Kinase CProtein TransportReceptors, N-Methyl-D-AspartateCalcium Channels, L-TypeProtein Kinase CReceptors, N-Methyl-D-Aspartategabapentingabapentinoidneuropathic painNMDA receptorphosphorylationsignal transductionsynaptic plasticity

Identifiers

PMID34252035
PMCPMC8318084
OpenAlexW3176615134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.