ArticleVirulence2021
Synergy of alanine and gentamicin to reduce nitric oxide for elevating killing efficacy to antibiotic-resistant
Article in Virulence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- Metabolic adaptations in antibiotic-resistantMicrobiology spectrum · 2026Article
- Proline Potentiates Aminoglycoside Bactericidal Efficacy AgainstLife (Basel, Switzerland) · 2026Article
- Metabolic activation of pyruvate cycle by protocatechualdehyde triggers oxidative killing of ampicillin-resistantMicrobiology spectrum · 2026Article
- Article
- Adenosine Monophosphate as a Metabolic Adjuvant Enhances Antibiotic Efficacy against Drug-Resistant Bacterial Pathogens.Pharmaceuticals (Basel, Switzerland) · 2024Article
- The nitric oxide paradox: antimicrobial and inhibitor of antibiotic efficacy.Emerging topics in life sciences · 2024Article
- Pyruvate Abundance Confounds Aminoglycoside Killing of Multidrug-Resistant Bacteria via Glutathione Metabolism.Research (Washington, D.C.) · 2024Article
- Role of Metabolic Adaptation ofPathogens (Basel, Switzerland) · 2023Review
- Aspartate metabolic flux promotes nitric oxide to eliminate both antibiotic-sensitive and -resistantFrontiers in immunology · 2023Article
- Alanine-mediated P cycle boosting enhances the killing efficiency of kasugamycin on antibiotic-resistantFrontiers in microbiology · 2023Article
- A mini-review: environmental and metabolic factors affecting aminoglycoside efficacy.World journal of microbiology & biotechnology · 2022Review
- Effects of l-Serine on Macrolide Resistance in Streptococcus suis.Microbiology spectrum · 2022Article
- Nitrite Promotes ROS Production to Potentiate Cefoperazone-Sulbactam-Mediated Elimination to Lab-Evolved and Clinical-Evolved Pseudomonas aeruginosa.Microbiology spectrum · 2022Article
- Exogenous Alanine Reverses the Bacterial Resistance to Zhongshengmycin with the Promotion of the P Cycle inAntibiotics (Basel, Switzerland) · 2022Article
- Fructose Promotes Crucian Carp Survival AgainstFrontiers in immunology · 2022Article
- Enhanced Biosynthesis of Fatty Acids Contributes to Ciprofloxacin Resistance inFrontiers in microbiology · 2022Article
- A Microtitre Plate Dilution Method for Minimum Killing Concentration Is Developed to Evaluate Metabolites-Enabled Killing of Bacteria by β-lactam Antibiotics.Frontiers in molecular biosciences · 2022Article
- Metabolomics-Driven Exploration of the Antibacterial Activity and Mechanism of 2-Methoxycinnamaldehyde.Frontiers in microbiology · 2022Article
- Article
- Functional proteomics identify mannitol metabolism in serum resistance and therapeutic implications inFrontiers in immunology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study explored the cooperative effect of both alanine (Ala) and gentamicin (Gent) on metabolic mechanisms by which exogenous Ala potentiates Gent to kill antibiotic-resistant
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.