Evidence map›Paper›PMID 34251961›Full record

ArticleBioengineered2021

MicroRNA-30b-5p promotes the proliferation and migration of human airway smooth muscle cells induced by platelet-derived growth factor by targeting phosphatase and tensin homolog deleted on chromosome ten.

Wentao Wang, Jian Guo, Yan Wang

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Noncoding RNAs in asthmatic airway smooth muscle cells.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  6. Article
  7. Recent miRNA Research in Asthma.Current allergy and asthma reports · 2022
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wentao WangDepartment of Pediatrics, Affiliated Hospital of Chengde Medical University, Chengde City, Hebei Province, China.ORCID 0000-0001-6699-0463
Jian GuoDepartment of Neonatology, Affiliated Hospital of Chengde Medical University, Chengde City, Hebei Province, China.
Yan WangDepartment of Pediatrics, Affiliated Hospital of Chengde Medical University, Chengde City, Hebei Province, China.
Chengde Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysfunction of airway smooth muscle (ASM) cells is crucial in asthma pathogenesis. Here, microRNA-30b-5p (miR-30b-5p)'s function and mechanism in ASM cells' multiplication and migration were investigated. Microarray was utilized for identifying the differentially expressed miRNAs in the bronchial epithelial cells of the asthma patients and healthy controls. Platelet-derived growth factor (PDGF) was employed to treat ASM cells to establish an

Indexed as

AsthmaCell LineCell MovementCell ProliferationHumansMicroRNAsMyocytes, Smooth MusclePlatelet-Derived Growth FactorPTEN PhosphohydrolaseMicroRNAsMIRN30a microRNA, humanPlatelet-Derived Growth FactorPTEN PhosphohydrolasePTEN protein, humanAirway smooth muscle cellasthmacell migrationcell proliferationmiR-30b-5pPTEN

Identifiers

PMID34251961
PMCPMC8806833
OpenAlexW3180876179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.