ArticleJournal of applied microbiology2022
Postmortem interval assessment by MALDI-TOF mass spectrometry analysis in murine cadavers.
Article in Journal of applied microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Microbial succession and machine learning for postmortem interval estimation in bromadiolone-poisoned cadavers.AMB Express · 2026Article
- Influence of Drugs and Toxins on Decomposition Dynamics: Forensic Implications.Molecules (Basel, Switzerland) · 2024Review
- Estimating postmortem interval based on oral microbial community succession in rat cadavers.Heliyon · 2024Article
- The Future Is Now: Unraveling the Expanding Potential of Human (Necro)Microbiome in Forensic Investigations.Microorganisms · 2023Review
- Repurposing Selamectin as an Antimicrobial Drug against Hospital-AcquiredMicroorganisms · 2023Article
- Viral Infection and Antiviral Treatments in Ocular Pathologies.Microorganisms · 2022Review
- Post-Mortem Interval and Microbiome Analysis through 16S rRNA Analysis: A Systematic Review.Diagnostics (Basel, Switzerland) · 2022Review
- Antiviral Activity ofViruses · 2022Article
- In Vitro Antibacterial and Anti-Inflammatory Activity ofPharmaceutics · 2022Article
- Postmortem Bacteriology in Forensic Autopsies-A Single Center Retrospective Study in Romania.Diagnostics (Basel, Switzerland) · 2022Article
- Impact ofPathogens (Basel, Switzerland) · 2022Article
- Characterization and Comparison of Ocular Surface Microbiome in Newborns.Microorganisms · 2022Article
- Niclosamide as a Repurposing Drug againstAntibiotics (Basel, Switzerland) · 2022Article
- MALDI-TOF Mass Spectrometry Analysis and Human Post-Mortem Microbial Community: A Pilot Study.International journal of environmental research and public health · 2022Article
- Postmortem interval assessment by MALDI-TOF mass spectrometry analysis in murine cadavers.Journal of applied microbiology · 2022Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThis study assessed the use of matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry as an alternative method to identify species associated with the thanatomicrobiota and epinecrotic communities. METHODS AND
resultsThe study was conducted on 10 murine cadavers, and microbiological swabs were collected from five external anatomical sites (eyes, ears, nose, mouth and rectum) and four internal organs (brain, spleen, liver, heart), during 16 and 30 days, for the thanatomicrobiota and epinecrotic communities, respectively. Our results revealed that the postmortem microbiota associated with the external cavities showed changes over time and reduced taxonomic diversity. The internal organs, initially sterile, showed signs of microbial invasion at 3 and 10 days postmortem for the liver-spleen and heart-brain, respectively. The postmortem microbiota was mainly dominated by Firmicutes and Proteobacteria.
conclusionsMALDI-TOF is a promising method for estimating postmortem interval (PMI), associated with rapid sample handling, good reproducibility and high productivity. SIGNIFICANCE AND IMPACT OF THE STUDY: This study investigated microbial changes during the decomposition process and proposed a simple strategy for PMI estimation. Results introducing the application of the MALDI-TOF method in the field of forensic.
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