ArticleChemistry (Weinheim an der Bergstrasse, Germany)2021
Targeted Chemical Modifications Identify Key Features of Carbohydrate Assemblies and Generate Tailored Carbohydrate Materials.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Neighboring Group Participation of Benzoyl Protecting Groups in C3- and C6-Fluorinated Glucose.European journal of organic chemistry · 2022Article
- Recent Advances in Electron Microscopy of Carbohydrate Nanoparticles.Frontiers in chemistry · 2022Review
- Targeted Chemical Modifications Identify Key Features of Carbohydrate Assemblies and Generate Tailored Carbohydrate Materials.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- The Flexibility of Oligosaccharides Unveiled Through Residual Dipolar Coupling Analysis.Frontiers in molecular biosciences · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The molecular level description of carbohydrate assemblies is hampered by their structural complexity and the lack of suitable analytical methods. Here, we employed systematic chemical modifications to identify key non-covalent interactions that triggered the supramolecular assembly of a disaccharide model. While some modifications disrupted the supramolecular organization, others were tolerated, delivering important information on the aggregation process. The screening identified new geometries, including nanotubes, and twisted ribbons that were characterized with electron tomography and electron diffraction (ED) methods. This work demonstrates that the combination of synthetic chemistry and ED methods is a powerful tool to draw correlations between the molecular structure and the nanoscale architecture of carbohydrate assemblies.
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Registered trials
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