Evidence map›Paper›PMID 34251616›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Co-expression Networks in Predicting Transcriptional Gene Regulation.

Synan F AbuQamar, Khaled A El-Tarabily, Arjun Sham

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Transcription-based comparison ofMicrobiology spectrum · 2026
    Article
  3. Review
  4. Transcriptome Analysis of Sesame (International journal of molecular sciences · 2024
    Article
  5. Article
  6. A Novel Role ofInternational journal of molecular sciences · 2023
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Synan F AbuQamarDepartment of Biology, College of Science, United Arab Emirates University, Al Ain, United Arab Emirates. sabuqamar@uaeu.ac.ae.
Khaled A El-TarabilyDepartment of Biology, College of Science, United Arab Emirates University, Al Ain, United Arab Emirates. ktarabily@uaeu.ac.ae.
Arjun ShamDepartment of Biology, College of Science, United Arab Emirates University, Al Ain, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent progress in transcriptomics and co-expression networks have enabled us to predict the inference of the biological functions of genes with the associated environmental stress. Microarrays and RNA sequencing (RNA-seq) are the most commonly used high-throughput gene expression platforms for detecting differentially expressed genes between two (or more) phenotypes. Gene co-expression networks (GCNs) are a systems biology method for capturing transcriptional patterns and predicting gene interactions into functional and regulatory relationships. Here, we describe the procedures and tools used to construct and analyze GCN and investigate the integration of transcriptional data with GCN to provide reliable information about the underlying biological mechanism.

Indexed as

AlgorithmsArabidopsisComputational BiologyGene Expression ProfilingGene Expression RegulationGene OntologyGene Regulatory NetworksMicroarray AnalysisPhenotypePrincipal Component AnalysisProtein Interaction MapsSoftwareBiological networksCo-expression networksNetwork analysisSystems biologyTarget gene identificationTranscriptomics

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.