ArticleThe international journal of cardiovascular imaging2021
Long term effects of mild severity COVID‑19 on right ventricular functions.
Article in The international journal of cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- A deeper look at long-term effects of COVID-19 on myocardial function in survivors with no prior heart diseases: a GRADE approach systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Normal reference values and determinants of right heart strain derived from speckle tracking echocardiography: a systematic review and meta-analysis.Quantitative imaging in medicine and surgery · 2026Article
- Cardiac structure and function 1.5 years after COVID-19: results from the EPILOC study.Infection · 2025Article
- Influence of the SARS-CoV-2 pandemic and infection on musculoskeletal function.Scientific reports · 2025Observational
- Rehabilitation in convalescent COVID-19 subjects improves right ventricular function.Cardiology journal · 2025Article
- Post-Acute Sequelae of Covid-19: A System-wise Approach on the Effects of Long-Covid-19.American journal of medicine open · 2024Review
- Cardiac Function and Structure before and after Mild SARS-CoV-2 Infection in Elite Athletes Using Biventricular and Left Atrial Strain.Biomedicines · 2024Article
- Clinical utility of ambulatory ECG monitoring and 2D-ventricular strain for evaluation of post-COVID-19 ventricular arrhythmia.BMC cardiovascular disorders · 2024Observational
- "When," "Where," and "How" of SARS-CoV-2 Infection Affects the Human Cardiovascular System: A Narrative Review.Balkan medical journal · 2024Review
- Medium- to long-term health condition of patients post-COVID-19, exercise intolerance and potential mechanisms: A narrative review and perspective.SAGE open medicine · 2024Review
- Mid-Regional Proadrenomedullin in COVID-19-May It Act as a Predictor of Prolonged Cardiovascular Complications?International journal of molecular sciences · 2023Review
- Beyond Acute COVID-19: A Review of Long-term Cardiovascular Outcomes.The Canadian journal of cardiology · 2023Review
- Strain Echocardiography in Acute COVID-19 and Post-COVID Syndrome: More than Just a Snapshot.Biomedicines · 2023Review
- Subclinical Myocardial Injury in Patients Recovered from COVID-19 Pneumonia: Predictors and Longitudinal Assessment.Journal of cardiovascular development and disease · 2023Article
- Coronary calcium score in COVID-19 survivors: Association with cardiac injury and cardiac function after 6 weeks.American heart journal plus : cardiology research and practice · 2023Article
- Myocardial function in COVID-19 patients after hospital discharge: a descriptive study comparing the first and second 'wave' patients.The international journal of cardiovascular imaging · 2022Article
- Screening for Myocardial Injury after Mild SARS-CoV-2 Infection with Advanced Transthoracic Echocardiography Modalities.Diagnostics (Basel, Switzerland) · 2022Article
- Cardiac impairments in postacute COVID-19 with sustained symptoms: A review of the literature and proof of concept.Physiological reports · 2022Review
- Relationship of right ventricular functions with in-hospital and 1 year later mortality in patients hospitalized for COVID-19 pneumonia.Annals of thoracic medicineArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronavirus disease 2019 (COVID-19) is a newly recognized infectious disease that has spread rapidly. COVID-19 has been associated with a number of cardiovascular involvements, including ventricular functions. The aim of our study was to evaluate the right ventricular functions of mild severity COVID-19 patients 3 months after, and compare them to the right ventricular functions of healthy volunteers. For this single-center study, data from 105 patients who were treated for mild severity COVID-19 between September 15, 2020 and December 31, 2020 were collected. 105 age and sex matched healthy subjects were included in the study. Right ventricular (RV) functions were evaluated using conventional two-dimensional (2D) echocardiography and 2D speckle-tracking echocardiography (STE) for all patients. 2D-E parameters indicating RV functions were compared between the two groups. RV diamaters, systolic pulmonary artery pressure (sPAP) and RV myocardial performance index (RV MPI) were significantly higher in the COVID-19 patients compared to control group (p < 0.05). Tricuspid annular plane systolic motion (TAPSE), right ventricular fractional area change (RVFAC) and RV S' were significantly lower in the COVID-19 group compared to control group (p < 0.05). RV global longitudinal strain (RV-GLS) (- 19.6 ± 5.2 vs. - 15.1 ± 3.4, p < 0.001) and RV free wall longitudinal strain RV-FWLS (- 19.6 ± 5.2 vs. - 17.2 ± 4.4, p < 0.001) values were significantly lower in the COVID-19 group than the control group. There was a significant negative correlation between RV-FWLS, RV-GLS and C-reactive protein (CRP), neutrophil to lymphocyte ratio (NLR), d-dimer, ferritin, platelet to lymphocyte ratio (PLR) in patients with mild severity COVID-19. This results suggested that RV-GLS and RV-FWLS decreased in the long term (third month) follow-up of patients treated for mild severity COVID-19 disease. Subclinical RV dysfunction may be observed in patients after mild severity COVID-19.
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