Evidence map›Paper›PMID 34251273›Full record

ArticleAmerican journal of physiology. Renal physiology2021

Ultrabright plasmonic fluor nanolabel-enabled detection of a urinary ER stress biomarker in autosomal dominant tubulointerstitial kidney disease.

Yeawon Kim, Zheyu Wang, Chuang Li, Kendrah Kidd, Yixuan Wang, Bryce G Johnson, Stanislav Kmoch, Jeremiah J Morrissey, Anthony J Bleyer, Jeremy S Duffield and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Yeawon KimDivision of Nephrology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri.
Zheyu WangDepartment of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, Missouri.
Chuang LiDivision of Nephrology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri.
Kendrah KiddSection of Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Yixuan WangDepartment of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, Missouri.
Bryce G JohnsonPfizer Worldwide Research and Development, Inflammation & Immunology, Cambridge, Massachusetts.
Stanislav KmochSection of Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Jeremiah J MorrisseyDivision of Clinical and Translational Research, Department of Anesthesiology, Washington University in St. Louis, St. Louis, Missouri.
Anthony J BleyerSection of Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Jeremy S DuffieldPrime Medicine Incorporated, Cambridge, Massachusetts.
Srikanth SingamaneniDepartment of Mechanical Engineering and Materials Science, Institute of Materials Science and Engineering, Washington University in St. Louis, St. Louis, Missouri.
Ying Maggie ChenDivision of Nephrology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri.ORCID 0000-0003-0994-8925
Washington University in St. Louis · USCharles University · CZPfizer (United States) · USWake Forest University · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
Resource Based Center for Musculoskeletal Biology and Medicine (Overall Application)P30AR074992 · NIAMS · WASHINGTON UNIVERSITY · PI MATTHEW J SILVA · 2019 to 2026
$6.8M
Therapeutics Development Core (Core B)P30DK114857 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GEORGE, ALFRED L., QUAGGIN, SUSAN E. · 2018 to 2022
$5.7M
The Role of the Osteoblast Secretome in Bone FormationP30AR057235 · NIAMS · WASHINGTON UNIVERSITY · PI SILVA, MATTHEW J · 2009 to 2018
$5.7M
PODOCYTE ENDOPLASMIC RETICULUM STRESS AND NEPHROTIC SYNDROMER01DK105056 · NIDDK · WASHINGTON UNIVERSITY · PI CHEN, YING MAGGIE · 2017 to 2025
$4.5M
Mutant Laminin Chains and Nephrotic SyndromeK08DK089015 · NIDDK · WASHINGTON UNIVERSITY · PI CHEN, YING MAGGIE · 2010 to 2014
$641k
PHARMACOLOGICAL RESCUE OF MUTANT LAMININ IN NEPHROTIC SYNDROMER03DK106451 · NIDDK · WASHINGTON UNIVERSITY · PI CHEN, YING MAGGIE · 2015 to 2016
$153k
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NIAMS NIH HHS P30 AR057235NIAMS NIH HHS P30 AR074992NIDDK NIH HHS K08 DK089015NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK114857NIDDK NIH HHS R01 DK105056NIDDK NIH HHS R03 DK106451
6 · The paper itself

Abstract

Autosomal dominant tubulointerstitial kidney disease (ADTKD)-uromodulin (

Indexed as

Immunosorbent TechniquesAnimalsBiomarkersEndoplasmic Reticulum Chaperone BiPEndoplasmic Reticulum StressHeat-Shock ProteinsHumansMiceNephritis, InterstitialUromodulinBiomarkersEndoplasmic Reticulum Chaperone BiPHeat-Shock ProteinsUromodulinautosomal dominant tubulointerstitial kidney diseasebiomarkerendoplasmic reticulum stressplasmon-enhanced fluorescence-linked immunosorbent assay

Identifiers

PMID34251273
PMCPMC8424663
OpenAlexW3179173089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.