ArticleOrganic letters2021
Carboxylic Acid Deoxyfluorination and One-Pot Amide Bond Formation Using Pentafluoropyridine (PFP).
Article in Organic letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Dimercaptosuccinic acid (DMSA) mono-esters and amides: synthesis and application in treating metal induced drug resistance in lung cancer.RSC medicinal chemistry · 2026Article
- Molecular engineering of bistetrafluoropyridine aryl ethers: a general platform for stable and programmable amorphous organic solids.RSC advances · 2026Article
- Synthesis ofThe Journal of organic chemistry · 2026Article
- Photoinduced Cleavage of Alkenyl Fluorides for Nucleophilic Acyl Substitution via In Situ Generated Acyl Fluorides.Organic letters · 2025Article
- Tin can milling: low-tech mechanochemical synthesis of plant-based prepolymers incorporating perfluoropyridine.RSC advances · 2025Article
- Article
- Recent advances in synthetic approaches for bioactive cinnamic acid derivatives.Beilstein journal of organic chemistry · 2025Review
- Chloroimidazolium Deoxyfluorination Reagent with HThe Journal of organic chemistry · 2024Article
- Halogenated Phenylpyridines Possessing Chemo-Selectivity for Diverse Molecular Architectures.ACS omega · 2024Article
- Rapid production of the anaesthetic mepivacaine through continuous, portable technology.Green chemistry : an international journal and green chemistry resource : GC · 2024Article
- Direct synthesis of acyl fluorides from carboxylic acids using benzothiazolium reagents.Beilstein journal of organic chemistry · 2024Article
- Fluorocarbonylation via palladium/phosphine synergistic catalysis.Nature communications · 2023Article
- Direct formation of amide/peptide bonds from carboxylic acids: no traditional coupling reagents, 1-pot, and green.Chemical science · 2023Article
- Functionalized Tetrazoles as Latent Active Esters in the Synthesis of Amide Bonds.Organic letters · 2022Article
- Nucleophilic Fluorination Catalyzed by a Cyclometallated Rhodium Complex.Organometallics · 2022Article
- Perfluoropyridine: Discovery, Chemistry, and Applications in Polymers and Material Science.Molecules (Basel, Switzerland) · 2022Review
- Perfluoroaryl and Perfluoroheteroaryl Reagents as Emerging New Tools for Peptide Synthesis, Modification and Bioconjugation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work describes the application of pentafluoropyridine (PFP), a cheap commercially available reagent, in the deoxyfluorination of carboxylic acids to acyl fluorides. The acyl fluorides can be formed from a range of acids under mild conditions. We also demonstrate that PFP can be utilized in a one-pot amide bond formation via
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Registered trials
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