Evidence map›Paper›PMID 34251046›Full record

ReviewBritish journal of clinical pharmacology2022

Health equality, race and pharmacogenomics.

Emma F Magavern, Deepti Gurdasani, Fu L Ng, Sandra Soo-Jin Lee

Abstract readReview
In one paragraph

Review in British journal of clinical pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
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  3. Review
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  12. Observational
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  19. Pre-emptive pharmacogenetic testing in the acute hospital setting: a cross-sectional study.QJM : monthly journal of the Association of Physicians · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emma F MagavernWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0003-0699-6411
Deepti GurdasaniWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Fu L NgDepartment of Clinical Pharmacology, St Georges University of London, London, UK.
Sandra Soo-Jin LeeDivision of Ethics, Department Medical Humanities and Ethics, Columbia University, New York, N.Y., USA.

Funding

The Ethics of Inclusion: Conceptualizing Diversity in Genomics ResearchR03HG010178 · NHGRI · STANFORD UNIVERSITY · PI LEE, SANDRA SOO-JIN · 2018 to 2019
$160k
Medical Research Council MR/S003711/1Medical Research Council MR/S003711/2NHGRI NIH HHS R03 HG010178
6 · The paper itself

Abstract

Pharmacogenomics is increasingly moving into mainstream clinical practice. Careful consideration must be paid to inclusion of diverse populations in research, translation and implementation, in the historical and social context of population stratification, to ensure that this leads to improvements in healthcare for all rather than increased health disparities. This review takes a broad and critical approach to the current role of diversity in pharmacogenomics and addresses potential pitfalls in order to raise awareness for prescribers. It also emphasizes evidence gaps and suggests approaches that may minimize negative consequences and promote health equality.

Indexed as

Health PromotionPharmacogeneticsHumansbioethicspharmacogenomicspharmacotherapytherapeutics

Identifiers

PMID34251046
PMCPMC8752640

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.