Evidence map›Paper›PMID 34250901›Full record

ArticleeLife2021

CTP promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional diffusion from

Francisco de Asis Balaguer, Clara Aicart-Ramos, Gemma Lm Fisher, Sara de Bragança, Eva M Martin-Cuevas, Cesar L Pastrana, Mark Simon Dillingham, Fernando Moreno-Herrero

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 65 citations in OpenAlex.

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  11. Expanding the diversity of bacterial DNA partitioning: A CTP-independent ParABProceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Francisco de Asis BalaguerDepartment of Macromolecular Structures, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.ORCID 0000-0002-6393-2863
Clara Aicart-RamosDepartment of Macromolecular Structures, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.ORCID 0000-0002-1114-4259
Gemma Lm FisherDNA:Protein Interactions Unit, School of Biochemistry, Biomedical Sciences Building, University of Bristol, University Walk, Bristol, United Kingdom.
Sara de BragançaDepartment of Macromolecular Structures, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.ORCID 0000-0003-4039-1993
Eva M Martin-CuevasDepartment of Macromolecular Structures, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Cesar L PastranaDepartment of Macromolecular Structures, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.ORCID 0000-0002-6988-8146
Mark Simon DillinghamDNA:Protein Interactions Unit, School of Biochemistry, Biomedical Sciences Building, University of Bristol, University Walk, Bristol, United Kingdom.ORCID 0000-0002-4612-7141
Fernando Moreno-HerreroDepartment of Macromolecular Structures, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.ORCID 0000-0003-4083-1709
Consejo Superior de Investigaciones Científicas · ESUniversity of Bristol · GB

Funding

Biotechnology and Biological Sciences Research CouncilEuropean Research Council 681299Wellcome TrustWellcome Trust 100401/Z/12/Z
6 · The paper itself

Abstract

Faithful segregation of bacterial chromosomes relies on the ParABS partitioning system and the SMC complex. In this work, we used single-molecule techniques to investigate the role of cytidine triphosphate (CTP) binding and hydrolysis in the critical interaction between centromere-like

Indexed as

BacteriaBacterial ProteinsCentromereChromosomes, BacterialChromosome SegregationCytidine TriphosphateDNA, BacterialHydrolysisProtein BindingPyrophosphatasesBacterial Proteinschromosome partition proteins, bacterialCTPaseCytidine TriphosphateDNA, BacterialPyrophosphatasesB. subtilischromosomeschromosome segregationgene expressionmagnetic tweezersmolecular biophysicsoptical tweezersParABS systemsParBsingle-molecule techniquesstructural biology

Identifiers

PMID34250901
PMCPMC8299390
OpenAlexW3182474345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.