Evidence map›Paper›PMID 34250813›Full record

Observational studyJournal of the American Heart Association2021

Caregiver Health-Related Quality of Life, Burden, and Patient Outcomes in Ambulatory Advanced Heart Failure: A Report From REVIVAL.

Nisha A Gilotra, Salpy V Pamboukian, Maria Mountis, Shawn W Robinson, Michelle Kittleson, Keyur B Shah, Rhondalyn C Forde-McLean, Donald C Haas, Douglas A Horstmanshof, Ulrich P Jorde and 11 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  5. Article
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  7. Observational
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 16 institutions in 1 country.

Nisha A GilotraJohns Hopkins Hospital Baltimore MD.
Salpy V PamboukianUniversity of Alabama Birmingham AL.
Maria MountisCleveland Clinic Foundation Cleveland OH.
Shawn W RobinsonUniversity of Maryland Medical Center Baltimore MD.
Michelle KittlesonSmidt Heart InstituteCedars-Sinai Medical Center Los Angeles CA.
Keyur B ShahVirginia Commonwealth University Richmond VA.
Rhondalyn C Forde-McLeanUniversity of Pennsylvania Philadelphia PA.
Donald C HaasAbington-Jefferson Health Abington PA.
Douglas A HorstmanshofIACC Advanced Cardiac Care Department INTEGRIS Baptist Medical Center Oklahoma City OK.
Ulrich P JordeMontefiore Medical Center Bronx NY.
Stuart D RussellDuke University School of Medicine Durham NC.
Wendy C Taddei-PetersDivision of Cardiovascular Sciences National Heart, Lung, and Blood Institute Bethesda MD.
Neal JeffriesDivision of Cardiovascular Sciences National Heart, Lung, and Blood Institute Bethesda MD.
Shokoufeh KhalatbariUniversity of MichiganMichigan Institute for Clinical and Health Research Ann Arbor MI.
Catherine A SpinoUniversity of MichiganSchool of Public Health Ann Arbor MI.
Blair RichardsUniversity of MichiganMichigan Institute for Clinical and Health Research Ann Arbor MI.
Matheos YosefUniversity of MichiganMichigan Institute for Clinical and Health Research Ann Arbor MI.
Douglas L MannWashington University St. Louis MO.
Garrick C StewartBrigham and Women's Hospital Boston MA.
Keith D AaronsonUniversity of Michigan Medical School Ann Arbor MI.
Kathleen L GradyFeinberg School of Medicine Northwestern University Chicago IL.
University of Michigan · USNational Heart Lung and Blood Institute · USBrigham and Women's Hospital · USCedars-Sinai Medical Center · USCleveland Clinic · USDuke University · USINTEGRIS Baptist Medical Center · USJohns Hopkins Hospital · USMontefiore Medical Center · USNorthwestern University · USThomas Jefferson University Hospital · USUniversity of Alabama · USUniversity of Maryland, Baltimore · USUniversity of Pennsylvania · USVirginia Commonwealth University · USWashington University in St. Louis · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
NCATS NIH HHS UL1 TR002240NHLBI NIH HHS HHSN268201100026C
6 · The paper itself

Abstract

Background Heart failure (HF) imposes significant burden on patients and caregivers. Longitudinal data on caregiver health-related quality of life (HRQOL) and burden in ambulatory advanced HF are limited. Methods and Results Ambulatory patients with advanced HF (n=400) and their participating caregivers (n=95) enrolled in REVIVAL (Registry Evaluation of Vital Information for VADs [Ventricular Assist Devices] in Ambulatory Life) were followed up for 24 months, or until patient death, left ventricular assist device implantation, heart transplantation, or loss to follow-up. Caregiver HRQOL (EuroQol Visual Analog Scale) and burden (Oberst Caregiving Burden Scale) did not change significantly from baseline to follow-up. At time of caregiver enrollment, better patient HRQOL by Kansas City Cardiomyopathy Questionnaire was associated with better caregiver HRQOL (

Indexed as

Quality of LifeAgedCaregiversCost of IllnessFemaleHeart-Assist DevicesHeart FailureHeart TransplantationHospitalizationHumansMaleMiddle AgedMultivariate AnalysisProspective StudiesRegistriesRegression Analysiscaregivingheart failureleft ventricular assist devicequality of life

Identifiers

PMID34250813
PMCPMC8483456
OpenAlexW3180244462

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.