ArticleJournal of veterinary internal medicine2021
Serum concentrations of canine pancreatic lipase immunoreactivity and C-reactive protein for monitoring disease progression in dogs with acute pancreatitis.
Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 42 citations in OpenAlex.
- Negative correlation between serial changes in the reticulocyte number and C-reactive protein level in dogs with delayed reticulocytosis.The Journal of veterinary medical science · 2026Article
- Creatinine-Derived Composite Indices for Improved Mortality Prediction in Dogs with Acute Pancreatitis.Animals : an open access journal from MDPI · 2026Article
- Clinical Utility of Adapted Modified Canine Activity Index (aMCAI) in Canine Acute Pancreatitis: A Prospective Observational Study.Animals : an open access journal from MDPI · 2026Article
- Diagnostic Value of Correlation Between Canine Chronic Enteropathy Clinical Activity Index (CCECAI) and Selected Hematological and Immunological Biomarkers in Dogs with Chronic Enteropathy: A Systematic Meta-Analysis.Veterinary sciences · 2026Article
- The comparison of acute phase proteins in experimentally induced canine acute pancreatitis.BMC veterinary research · 2026Article
- Comparative analysis of prognostic scoring systems for cats with suspected pancreatitis (472 cats).Journal of veterinary internal medicine · 2026Article
- Serum pancreatitis-associated protein 1 concentrations in dogs with acute signs of gastrointestinal disease and normal or abnormal DGGR lipase activity.Journal of veterinary internal medicine · 2026Article
- Prognostic utility of red blood cell distribution width-based ratios and their individual components for mortality prediction in dogs with acute pancreatitis.Frontiers in veterinary science · 2026Article
- Pilot Study: Association Between Surgical Severity and Postoperative Point-of-Care C-Reactive Protein Levels in Dogs Undergoing Orthopedic Surgery.Veterinary sciences · 2025Article
- Survival outcomes and prognostic indicators in canine pancreatitis: A retrospective cohort study of acute kidney injury and concurrent diseases.Veterinary world · 2025Article
- Treatment of canine pancreatitis using membrane-free stem cell extract and its anti-inflammatory effect.Frontiers in veterinary science · 2025Article
- Assessment of point-of-care quantitative serum canine pancreatic lipase testing for diagnosing acute pancreatitis in dogs.Frontiers in veterinary science · 2025Article
- Assessment of acute and chronic pain in canine internal medicine-what is missing in our diagnostic toolbox?Frontiers in veterinary science · 2025Article
- Allogenic Adipose-Derived Mesenchymal Stem Cell Infusion for the Management of Acute-Onset Pancreatitis in Dogs: A Pilot Study.Animals : an open access journal from MDPI · 2024Article
- Evaluation of Disease Spectrum in Hospitalized Cats with Hyperlipasemia: Pancreatitis Alone Is Rare, Hyperlipasemia without Suspected Pancreatitis Is Common.Animals : an open access journal from MDPI · 2024Article
- Serum αVeterinary sciences · 2023Article
- Utility of 1,2-o-dilauryl-rac-glycero glutaric acid-(6'-methylresorufin)-ester-lipase for monitoring dogs with chronic pancreatitis.Journal of veterinary internal medicine · 2023Article
- Evaluation of serum 25-hydroxyvitamin D, C-reactive protein, and haptoglobin as biomarkers in dogs newly diagnosed with histoplasmosis.Journal of veterinary internal medicine · 2023Article
- Evaluation of Host Constitutive and Ex Vivo Coccidioidal Antigen-Stimulated Immune Response in Dogs with Naturally Acquired Coccidioidomycosis.Journal of fungi (Basel, Switzerland) · 2023Article
- Cardiovascular abnormalities in dogs with acute pancreatitis.Journal of veterinary internal medicine · 2023Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundReliable biomarkers for monitoring disease progression and management in dogs with acute pancreatitis have not been described.
objectiveTo determine if serum concentrations of canine pancreatic lipase immunoreactivity (cPLI) and C-reactive protein (CRP) can be used as biomarkers for disease progression in hospitalized dogs with acute pancreatitis. ANIMALS: Thirteen hospitalized dogs with acute pancreatitis diagnosed based on clinical signs, serum cPLI concentrations, and imaging findings were enrolled.
methodsSerum cPLI and CRP concentrations were determined before and then daily during hospital management and 1 week after hospital discharge. Modified canine activity index (MCAI) and canine acute pancreatitis clinical severity index (CAPCSI) scores were calculated daily for each patient while hospitalized.
resultsThe MCAI scores (P = .03) but not CAPCSI scores (P = .31) were significantly different between dogs that survived to discharge (n = 11) and those that did not (n = 2). Serum cPLI concentration was positively correlated with MCAI (rho = 0.42; P = .01). Serum CRP concentration also was positively correlated with the MCAI (rho = 0.42, P = .01).
conclusionsSerum cPLI and possibly CRP could be used as objective biomarkers for clinical changes in hospitalized dogs with acute pancreatitis. Additional studies involving larger numbers of dogs would be warranted to evaluate the broader impact of these findings.
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