Evidence map›Paper›PMID 34250647›Full record

ArticleJournal of cardiac surgery2021

Incidence and predictors of permanent pacemaker implantation after surgical aortic v alve replacement: Data of the Netherlands Heart Registration (NHR).

Justine M Ravaux, Sander Mj Van Kuijk, Michele Di Mauro, Kevin Vernooy, Elham Bidar, Silvia Mariani, Giulia Actis Dato, Arnoud W Van T Hof, Leo Veenstra, Suzanne Kats and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of cardiac surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Justine M RavauxDepartment of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Sander Mj Van KuijkDepartment of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Michele Di MauroDepartment of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.ORCID http://orcid.org/0000-0003-2611-5626
Kevin VernooyDepartment of Cardiology, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Elham BidarDepartment of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Silvia MarianiDepartment of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Giulia Actis DatoDepartment of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Arnoud W Van T HofDepartment of Cardiology, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Leo VeenstraDepartment of Cardiology, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Suzanne KatsDepartment of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Saskia HoutermanNetherlands Heart Registration (NHR), Utrecht, The Netherlands.
Jos G MaessenDepartment of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Roberto LorussoDepartment of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
Cardiothoracic Surgery Registration Committee of the Netherlands Heart RegistrationSee addendum for Cardiothoracic Surgery Registration Committee members of the Netherlands Heart Registration.
Maastricht University Medical Centre · NLNetherlands Heart Registration · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePermanent pacemaker implantation (PPI) after surgical aortic valve replacement (SAVR) remains a frequent complication. Predictors, however, have been mainly investigated in single-center studies. Therefore, nationwide data were used to identify patients-and procedural risk factors for postoperative PPI. MATERIALS AND

methodsData were retrospectively collected from the Netherlands Heart Registration (NHR). Patients enrolled in the NHR undergoing isolated SAVR from 2013 to 2019 were analyzed. Primary endpoint was in-hospital PPI during hospitalization after SAVR.

resultsFrom the NHR database, 5600 patients with symptomatic aortic valve stenosis were included in the study. Crude incidence of post-SAVR PPI was 4.0%. Backward regression analysis identified previous cardiac surgery (odds ratio [OR]: 1.80; 95% confidence interval [CI]: 1.18-2.76), extra-corporeal circulation time (OR: 1.01; 95% CI: 1.00-1.01), vasopressor use (OR: 2.66; 95% CI: 1.79-3.96) and in-hospital cardiac conduction abnormalities (OR: 4.48; 95% CI: 3.36-5.98) as potential predictors for PPI. Across the time, PPI after SAVR significantly increased (OR: 1.11; 95% CI: 1.03-1.21).

conclusionsFrom this nationwide analysis, PPI after SAVR remains a low but increasingly frequent complication. Several predictive factors for postoperative PPI after SAVR have been identified and might be useful for patient informed consent about potential adverse event rate.

Indexed as

Aortic Valve StenosisHeart Valve Prosthesis ImplantationPacemaker, ArtificialTranscatheter Aortic Valve ReplacementAortic ValveHumansIncidenceNetherlandsRetrospective StudiesRisk FactorsTreatment Outcomeaortic stenosispermanent pacemaker implantationsurgical aortic valve replacement

Identifiers

PMID34250647
PMCPMC8518121
OpenAlexW3177766411

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.