Evidence map›Paper›PMID 34250492›Full record

ArticleRadiology. Cardiothoracic imaging2021

T2-weighted Lung Imaging Using a 0.55-T MRI System.

Adrienne E Campbell-Washburn, Ashkan A Malayeri, Elizabeth C Jones, Joel Moss, Kevin P Fennelly, Kenneth N Olivier, Marcus Y Chen

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03331380 (Technical Development of Cardiovascular Magnetic Resonance Imaging), which is not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03331380 narecruitingnot on this map

Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System

TypeinterventionalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran2018 to 2028Enrolled2,950ConditionsCADArmsMRI scan - obj 1, MRI scans - obj 2, MRI scans - obj 3, MRI scans - obj 4
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Society for Cardiovascular Magnetic Resonance recommendations toward environmentally sustainable cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Guideline
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Magnetic resonance imaging.Science advances · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Adrienne E Campbell-WashburnCardiovascular (A.E.C.W., M.Y.C.) and Pulmonary (J.M., K.P.F., K.N.O.) Branches, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Department of Health and Human Services, Bethesda, Md (A.A.M., E.C.J.).ORCID 0000-0002-7169-5693
Ashkan A MalayeriCardiovascular (A.E.C.W., M.Y.C.) and Pulmonary (J.M., K.P.F., K.N.O.) Branches, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Department of Health and Human Services, Bethesda, Md (A.A.M., E.C.J.).ORCID 0000-0002-4442-7343
Elizabeth C JonesCardiovascular (A.E.C.W., M.Y.C.) and Pulmonary (J.M., K.P.F., K.N.O.) Branches, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Department of Health and Human Services, Bethesda, Md (A.A.M., E.C.J.).
Joel MossCardiovascular (A.E.C.W., M.Y.C.) and Pulmonary (J.M., K.P.F., K.N.O.) Branches, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Department of Health and Human Services, Bethesda, Md (A.A.M., E.C.J.).
Kevin P FennellyCardiovascular (A.E.C.W., M.Y.C.) and Pulmonary (J.M., K.P.F., K.N.O.) Branches, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Department of Health and Human Services, Bethesda, Md (A.A.M., E.C.J.).
Kenneth N OlivierCardiovascular (A.E.C.W., M.Y.C.) and Pulmonary (J.M., K.P.F., K.N.O.) Branches, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Department of Health and Human Services, Bethesda, Md (A.A.M., E.C.J.).
Marcus Y ChenCardiovascular (A.E.C.W., M.Y.C.) and Pulmonary (J.M., K.P.F., K.N.O.) Branches, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Department of Health and Human Services, Bethesda, Md (A.A.M., E.C.J.).ORCID https://orcid.org/0000-0003-0743-9369
National Institutes of Health · US

Funding

Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)ZIAHL002541 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI MOSS, JOEL · 2009 to 2025
$47.7M
Bronchiectasis and chronic airway infectionZIAHL006200 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI FENNELLY, KEVIN · 2015 to 2025
$25.1M
Cardiovascular CT Clinical ResearchZIAHL006220 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHEN, MARCUS · 2017 to 2025
$22.5M
Pulmonary clinical medicine: PFT lab, bronchoscopy, consultation services, and educationZIDHL006202 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI MASUR, HENRY · 2015 to 2025
$11.0M
Development of high-performance low field MRI technology ZIAHL006257 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CAMPBELL-WASHBURN, ADRIENNE · 2021 to 2025
$8.1M
Inflammatory and immune dysregulation associated lung diseaseZIAHL006201 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI OLIVIER, KENNETH · 2015 to 2022
$2.1M
6 · The paper itself

Abstract

purposeTo assess a 0.55-T MRI system for imaging lung disease and to compare image quality with clinical CT scans. MATERIALS AND

methodsIn this prospective study conducted between November 2018 and December 2019, respiratory-triggered T2-weighted turbo spin-echo MRI at 0.55 T was compared with clinical CT scans in 24 participants (mean age, 59 years ± 16 [standard deviation]; 18 women) with common lung abnormalities. MR images were reviewed and scored by experienced readers. Abnormal findings identified with MRI and CT were compared using the Cohen κ statistic.

resultsHigh-quality structural pulmonary MR images were attained with an average acquisition time of 11 minutes ± 3. MRI generated sufficient image quality to robustly detect bronchiectasis (κ = 0.61), consolidative opacities (κ = 1.00), cavitary lesions (κ = 1.00), effusion (κ = 0.64), mucus plug (κ = 0.68), and solid scattered nodularity (κ = 0.82). Diffuse disease, including ground-glass opacities (κ = 0.57) and tree-in-bud nodules (κ = 0.48), were the findings that were most difficult to discern using MRI, with false readings in four of 18 patients for each feature. Nodule size, which was measured independently at CT and MRI, was strongly correlated (

conclusionThis initial study indicates that high-performance 0.55-T MRI holds promise in the evaluation of common lung disease.Clinical trials registration no. NCT03331380

Identifiers

PMID34250492
PMCPMC8259660
OpenAlexW3168738729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.