ArticleACS omega2021
Model for Gold Nanoparticle Synthesis: Effect of pH and Reaction Time.
Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.
- Exploring the role of density functional theory in the design of gold nanoparticles for targeted drug delivery: a systematic review.Journal of molecular modeling · 2025Pooled it
- Multimodal Characterization of Acerola-Derived Gold Nanoparticles through Integrated Advanced Distributional Analysis.ACS omega · 2026Article
- Injectable Artificial Photoreceptors: STEM Cell Functional Integration and in vivo Electrophysiological Validation in Retinal Degeneration Models.Small science · 2026Article
- Study of pH Role in the Green Synthesis of Gold Nanoparticles: From Reduction to Size and Shape Control.Materials (Basel, Switzerland) · 2026Article
- Gold nanoparticle arrays using pre-patterned silicon substrates.Discover nano · 2026Article
- Mechanistic advances in microbial nanobiotechnology and their applications in sustainable agriculture, environment and biomedicine.Discover nano · 2026Review
- DoE-It-Yourself (DoEIY): An Open-Access Web Application for Democratizing Experimental Design in Chemical and Materials Research.Small methods · 2026Article
- Assessment of Hairpin-Functionalization of Gold Nanoparticles toward a Facile Detection of Zika Virus and Lineage Identification.ACS omega · 2025Article
- Vitamin-Conjugated Metallic Nanoparticles: Applications for Antimicrobial and Anti-Cancer Drug Delivery.Molecules (Basel, Switzerland) · 2025Review
- Biogenically forged ZnO nanoparticles usingRSC advances · 2025Article
- Tailoring color and antibacterial properties of cotton fabric materials using gold nanoparticles synthesized from Mangifera indica peel extract.Scientific reports · 2025Article
- Toxicity analysis of gold nanoparticle formulations used for intraocular applications.Scientific reports · 2025Article
- Biogenic copper and copper oxide nanoparticles to combat multidrug-resistantBiotechnology reports (Amsterdam, Netherlands) · 2025Review
- Article
- One step synthesis of ultrafine PHF@AuNPs nanocomposite and its application in NIR triggered photodynamic therapy.PloS one · 2025Article
- Article
- Probing electronic-structure pH-dependency of Au nanoparticles through X-ray Absorption Spectroscopy.Scientific reports · 2024Article
- Optimization of Paper-Based Alveolar-Mimicking SERS Sensor for High-Sensitivity Detection of Antifungal Agent.Biosensors · 2024Article
- Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future Prospects.Nanomaterials (Basel, Switzerland) · 2024Review
- Updated Review of Metal Nanoparticles Fabricated by Green Chemistry Using Natural Extracts: Biosynthesis, Mechanisms, and Applications.Bioengineering (Basel, Switzerland) · 2024Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The synthesis of gold nanoparticles is dependent on both the concentration of trisodium citrate dihydrate and the time that it interacts with tetrachloroauric acid. A wide range of gold nanoparticles with various sizes and dispersity can be produced based on control variables, such as time of reaction and acid concentration, using a similar approach to that of the Turkevich model. In this model, the pH of the solution decreases slightly throughout the reaction (0.005 unit/min) due to the chemical interactions between trisodium citrate dihydrate and tetrachloroauric acid. Dicarboxy acetone is formed during citrate oxidization, resulting in gold nuclei formation over time. In addition, gold nanoparticle nucleation causes pH fluctuation over time based on gold nanoparticle sizes. An inverse correlation (coefficient of smaller than -0.97) was calculated between the pH and reaction time at different ratios of trisodium citrate dihydrate to tetrachloroauric acid. Regression analysis was used to develop a model for the prediction of the size of gold nanoparticles ranging from 18 to 38 nm based on the concentration of trisodium citrate dihydrate and the reaction time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.