Evidence map›Paper›PMID 34250335›Full record

ArticleACS omega2021

Efficient Access to the Iboga Skeleton: Optimized Procedure to Obtain Voacangine from

Bruno González, Catherine Fagúndez, Alejandro Peixoto de Abreu Lima, Leopoldo Suescun, Diver Sellanes, Gustavo A Seoane, Ignacio Carrera

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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  6. 5-HTInternational journal of molecular sciences · 2024
    Article
  7. Validated QuantitativeACS omega · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bruno GonzálezLaboratorio de Síntesis Orgánica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, 11800 Montevideo, Uruguay.ORCID https://orcid.org/0000-0003-2854-0714
Catherine FagúndezLaboratorio de Síntesis Orgánica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, 11800 Montevideo, Uruguay.
Alejandro Peixoto de Abreu LimaLaboratorio de Síntesis Orgánica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, 11800 Montevideo, Uruguay.
Leopoldo SuescunLaboratorio de Cristalografía, Química del Estado Sólido y Materiales, Departamento de Experimentación y Teoría de la Estructura de la Materia y sus Aplicaciones, Facultad de Química, Universidad de la República, 11800 Montevideo, Uruguay.ORCID https://orcid.org/0000-0002-7606-8074
Diver SellanesSiquimia SRL, Instituto Polo Tecnológico de Pando, Facultad de Química, Universidad de la República, 91000 Montevideo, Uruguay.
Gustavo A SeoaneLaboratorio de Síntesis Orgánica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, 11800 Montevideo, Uruguay.ORCID https://orcid.org/0000-0003-2126-8551
Ignacio CarreraLaboratorio de Síntesis Orgánica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, 11800 Montevideo, Uruguay.ORCID https://orcid.org/0000-0002-6053-3162
Universidad de la República de Uruguay · UY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iboga alkaloids are a group of monoterpenoid indole alkaloids with promising and intriguing biological activities. Ibogaine is the representative member of the series and has become widely known as a potent atypical psychedelic with promising effects to treat substance use disorder. Nowadays, an efficient and scalable enantioselective total synthesis of ibogaine and related iboga alkaloids is still lacking, so direct extraction from natural sources or semi-synthetic schemes are the methods of choice to obtain them in a preparative scale. In particular, ibogaine can be obtained either by a low yielding direct isolation from

Identifiers

PMID34250335
PMCPMC8264847
OpenAlexW3175128856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.