Evidence map›Paper›PMID 34250326›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2021

A Clinically Driven Task-Based Comparison of Photon Counting and Conventional Energy Integrating CT for Soft Tissue, Vascular, and High-Resolution Tasks.

Jayasai R Rajagopal, Pooyan Sahbaee, Faraz Farhadi, Justin B Solomon, Juan Carlos Ramirez-Giraldo, William F Pritchard, Bradford J Wood, Elizabeth C Jones, Ehsan Samei

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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  6. Development of a separability index for task specific characterization of spectral computed tomography.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2024
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  7. Article
  8. Impact of the confluence of cardiac motion and high spatial resolution on performance of ECG-gated imaging with an investigational photon-counting CT system: A phantom study.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jayasai R RajagopalCarl E. Ravin Advanced Imaging Laboratories, and Medical Physics Graduate Program, Duke University, Durham, NC, 27705 USA.
Pooyan SahbaeeSiemens Medical Solutions USA, Malvern, PA, 19355 USA.
Faraz FarhadiRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD 20892 USA.
Justin B SolomonCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, and Department of Radiology, Duke University, Durham NC, 27705 USA.
Juan Carlos Ramirez-GiraldoSiemens Medical Solutions USA, Malvern, PA, 19355 USA.
William F PritchardCenter for Interventional Oncology, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda MD, 20892 USA.
Bradford J WoodCenter for Interventional Oncology, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, 20892 USA.
Elizabeth C JonesRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD 20892 USA.
Ehsan SameiCarl. E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, and Departments of Electrical and Computer Engineering, Radiology, Biomedical Engineering, and Physics, Duke University, Durham, NC, 27705 USA.
National Institutes of Health Clinical Center · USDuke University · USSiemens Healthcare (United States) · US

Funding

Center for Interventional OncologyZIDBC011242 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WOOD, BRADFORD J · 2009 to 2025
$18.7M
TR&D Project 3: Virtual ReadersP41EB028744 · NIBIB · DUKE UNIVERSITY · PI Ehsan Samei · 2021 to 2026
$7.8M
Simulation Tools for Dynamic CTR01EB001838 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI SAMEI, EHSAN, SEGARS, WILLIAM P · 2005 to 2023
$6.9M
Interventional OncologyZIACL040015 · CLC · CLINICAL CENTER · PI WOOD, BRADFORD · 2009 to 2025
$0k
Translational Development of Photon-Counting CT ImagingZIACL040017 · CLC · CLINICAL CENTER · PI JONES, ELIZABETH C. · 2020 to 2022
$0k
Intramural NIH HHS Z99 CL999999Intramural NIH HHS ZIA CL040015Intramural NIH HHS ZID BC011242NIBIB NIH HHS P41 EB028744NIBIB NIH HHS R01 EB001838
6 · The paper itself

Abstract

Photon-counting CT detectors are the next step in advancing CT system development and will replace the current energy integrating detectors (EID) in CT systems in the near future. In this context, the performance of PCCT was compared to EID CT for three clinically relevant tasks: abdominal soft tissue imaging, where differentiating low contrast features is important; vascular imaging, where iodine detectability is critical; and, high-resolution skeletal and lung imaging. A multi-tiered phantom was imaged on an investigational clinical PCCT system (Siemens Healthineers) across different doses using three imaging modes: macro and ultra-high resolution (UHR) PCCT modes and EID CT. Images were reconstructed using filtered backprojection and soft tissue (B30f), vascular (B46f), or high-resolution (B70f; U70f for UHR) kernels. Noise power spectra, task transfer functions, and detectability index were evaluated. For a soft tissue task, PCCT modes showed comparable noise and resolution with improved contrast-to-noise ratio. For a vascular task, PCCT modes showed lower noise and improved iodine detectability. For a high resolution task, macro mode showed lower noise and comparable resolution while UHR mode showed higher noise but improved spatial resolution for both air and bone. PCCT offers competitive advantages to EID CT for clinical tasks.

Indexed as

clinical imaging systemsenergy integrating detectorimage qualityphantomphotodetector technologyphoton-counting CTtask based

Identifiers

PMID34250326
PMCPMC8269971
OpenAlexW3082235879

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.