Evidence map›Paper›PMID 34250266›Full record

ArticleWellcome open research2021

WOMAN-PharmacoTXA trial: Study protocol for a randomised controlled trial to assess the pharmacokinetics and pharmacodynamics of intramuscular, intravenous and oral administration of tranexamic acid in women giving birth by caesarean section.

Monica Arribas, Ian Roberts, Rizwana Chaudhri, Amber Geer, Danielle Prowse, Mwansa Ketty Lubeya, Aasia Kayani, Kiran Javaid, Stanislas Grassin-Delyle, Haleema Shakur-Still

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Review
  3. Improving Development of Drug Treatments for Pregnant Women and the Fetus.Therapeutic innovation & regulatory science · 2022
    Review
  4. Innovations in the prevention and treatment of postpartum hemorrhage: Analysis of a novel medicines development pipeline database.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022
    Article
  5. Alternative routes to intravenous tranexamic acid for postpartum hemorrhage: A systematic search and narrative review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Monica ArribasClinical Trials Unit, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.ORCID https://orcid.org/0000-0002-1405-9391
Ian RobertsClinical Trials Unit, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.ORCID https://orcid.org/0000-0003-1596-6054
Rizwana ChaudhriGlobal Institute of Human Development, Shifa Tameer-e-Millat University, Islamabad, H-8, Pakistan.ORCID https://orcid.org/0000-0002-5428-3988
Amber GeerClinical Trials Unit, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Danielle ProwseClinical Trials Unit, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Mwansa Ketty LubeyaWomen and Newborn Hospital, University Teaching Hospital, Nationalist Road, Lusaka, PB RW1X, Zambia.
Aasia KayaniGlobal Institute of Human Development, Shifa Tameer-e-Millat University, Islamabad, H-8, Pakistan.
Kiran JavaidGlobal Institute of Human Development, Shifa Tameer-e-Millat University, Islamabad, H-8, Pakistan.
Stanislas Grassin-DelyleDépartement de Biotechnologie de la Santé, Université Paris-Saclay, UVSQ, Inserm, Infection et inflammation, Montigny le Bretonneux, France.ORCID https://orcid.org/0000-0001-5747-4432
Haleema Shakur-StillClinical Trials Unit, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.ORCID https://orcid.org/0000-0002-6511-109X
London School of Hygiene & Tropical Medicine · GBShifa Tameer-e-Millat University · PKInserm · FRUniversity Teaching Hospital · ZM

Funding

Medical Research Council MR/M009211/1Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antifibrinolyticcaesarean sectionclinical trialintramuscularoralPharmacodynamicsPharmacokineticsPPHTranexamic acid

Identifiers

PMID34250266
PMCPMC8264807
OpenAlexW3170107918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.