Evidence map›Paper›PMID 34250253›Full record

ArticleOpen medicine (Warsaw, Poland)2021

Association between Tfh and PGA in children with Henoch-Schönlein purpura.

Miao Meihua, Li Xiaozhong, Wang Qin, Zhu Yunfen, Cui Yanyan, Shao Xunjun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open medicine (Warsaw, Poland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Miao MeihuaDepartment of Clinical Laboratory, Children's Hospital of Soochow University, Suzhou 215025, China.
Li XiaozhongDepartment of Clinical Laboratory, Children's Hospital of Soochow University, Suzhou 215025, China.
Wang QinDepartment of Immunology, School of Biology & Basic Medical Science, Soochow University, Suzhou 215021, China.
Zhu YunfenDepartment of Clinical Laboratory, Children's Hospital of Soochow University, Suzhou 215025, China.
Cui YanyanDepartment of Clinical Laboratory, Children's Hospital of Soochow University, Suzhou 215025, China.
Shao XunjunDepartment of Clinical Laboratory, Children's Hospital of Soochow University, Suzhou 215025, China.
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate the roles of follicular helper CD4

methodsELISA was performed to determine serum PGA-IgA and PGA-IgG. Flow cytometry was utilized to determine the peripheral CD4

resultsCompared with the cases with acute respiratory infection and elective surgery, the proportion of CD4

conclusionIncreased activity of Tfh cells, which is closely related to mucosal immunity, may be a major contributor in the elevation of PGA-IgA, and Tfh cells and PGA-IgA are closely related to the occurrence of HSP.

Indexed as

follicular helper CD4+ T cellsHenoch–Schönlein purpuraimmunityα-1,4-d-polygalacturonic acid

Identifiers

PMID34250253
PMCPMC8254571
OpenAlexW3180920364

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.